Anti-Human FGFR2 Recombinant Antibody (Atto-MuMab-01)

Name: Anti-Human FGFR2 Recombinant Antibody (Atto-MuMab-01)
SKU: TAB-059WM
Rating: 5 (1 reviews)

CAT#: TAB-059WM

Atto-MuMab-01 is a human IgG1 isotype and can elicit strong immune responses of antibody-dependent cellular cytotoxicity (ADCC) and complement-mediated cell lysis. And Atto-MuMab-01 can be a potentially therapeutic agent in prostate cancer.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEK 293

Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm, cell junctions & vesicles.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/if_selected.jpg

Normal Tissue Figure 2 IHC staining of human stomach

Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/ihc_selected.jpg

Normal Tissue Figure 3 IHC staining of human skin

Immunohistochemical staining of human skin shows strong ctyoplasmic positivity in keratinocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_1_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_5.jpg

Normal Tissue Figure 5 Colon

Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_7_3.jpg

Normal Tissue Figure 6 Testis

Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_4_6.jpg

Normal Tissue Figure 7 Lymph node

Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_9_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (AN3-CA, BEWO, CACO-2, HaCaT, HAP1, NTERA-2, T-47d)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000066468-FGFR2

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Specifications

Immunogen
FGFR2: isoform FGFR2-IIIc

Host Species
Mouse

Specificity
Human

Species Reactivity
Human

Clone
Atto-MuMab-01

Applications
ELISA, WB, FC

Related Disease
Prostate Cancer

Target

Alternative Names
FGFR2; fibroblast growth factor receptor 2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14

Gene ID
2263

UniProt ID
P21802

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Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-059WM.pdf

MSDS

MSDS - TAB-059WM.pdf

COA

Certificate of Analysis Lookup

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