Anti-GD2 Recombinant Antibody (Dinutuximab)

Recombinant chimeric (human/Mouse) antibody expressed in CHO binding to human GD2. Dinutuximab is a chimeric monoclonal antibody that induces antibody dependent cell-mediated cytotoxicity. Dinutuximab is intended as maintenance therapy (targeting minimal residual disease) for high risk neuroblastoma, administered after induction therapy, autologous stem cell transplantation and/or radiotherapy.

Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Mouse

Derivation
Chimeric (Human/Mouse)

Type
IgG1 - kappa

Species Reactivity
Human

Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.

Trade name
Unituxin

Generic Name
dinutuximab

Related Disease
Neuroblastoma

Product Property

Purity
>95.0% as determined by analysis by SDS-PAGE.

Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

Alternative Names
dinutuximab;Unituxin;Ch14.18;APN311;Disialoganglioside GD2;Ganglioside G2;GD2

Related Resources

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

See other products for "Dinutuximab"

See other products for "GD2"

Single-domain Antibody

CAT	Product Name	Application	Type
NAB-770-sdAb	Recombinant Anti-Human GD2 VHH Single Domain Antibody	Neut, ChiP, IP, FUNC	Llama VHH

Immunotoxin

CAT	Product Name	Application	Type
AGTO-L018R	anti-GD2 immunotoxin 14G2a (IgG)-RTA	Cytotoxicity assay, Functional assay

Humanized Antibody

CAT	Product Name	Application	Type
TAB-304CL	Anti-Human GD2 Recombinant Antibody (hu14.18K322A)	FC, FuncS	Antibody
PABX-059	Human Anti-GD2 Recombinant Antibody (PABX-059)	FuncS	IgG1, κ
PABX-059-F (E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (PABX-059-F (E))	FC, ELISA, FuncS	Human Fab

Recombinant Antibody

CAT	Product Name	Application	Type
PABL-100	Mouse Anti-GD2 Recombinant Antibody (clone 14G2a)	ELISA, WB, FuncS	Mouse IgG
FAMAB-0126YC	Mouse Anti-GD2 Recombinant Antibody (clone 7A4)	ELISA	Mouse IgG3, κ
HPAB-0701-CN	Human Anti-GD2 Recombinant Antibody (clone AB527)	ELISA, FC, IHC, IF	Human IgM
HPAB-0027-WJ	Mouse Anti-GD2 Recombinant Antibody (HPAB-0027-WJ)	ELISA, RIA	Mouse IgG3, κ
HPAB-1030WJ	Human Anti-GD2 Recombinant Antibody (HPAB-1030WJ)	ELISA	Chimeric (mouse/human) IgG

Fab Fragment Antibody

CAT	Product Name	Application	Type
PFBL-100	Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); Fab Fragment	ELISA, WB, FuncS	Mouse Fab
PFBL-101	Mouse Anti-GD2 Recombinant Antibody (clone 3F8); Fab Fragment	FC, ELISA, FuncS	Mouse Fab
PFBZ-049	Mouse Anti-GD2 Recombinant Antibody (clone ME36.1); Fab Fragment	WB, FuncS	Mouse Fab
HPAB-1524WJ-F(E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM8138)	ELISA, WB	Human Fab
HPAB-1525WJ-F(E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM1138)	ELISA, WB	Human Fab

Human Antibody

CAT	Product Name	Application	Type
TAB-074CQ-F(E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-074CQ-F(E))	ELISA, FC	Human Fab
TAB-075CQ-F(E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-075CQ-F(E))	ELISA, FC	Human Fab
TAB-076CQ-F(E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-076CQ-F(E))	ELISA, FC	Human Fab
TAB-077CQ-F(E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-077CQ-F(E))	ELISA, FC	Human Fab
TAB-078CQ-F(E)	Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-078CQ-F(E))	ELISA, FC	Human Fab

Neuroscience Antibody

CAT	Product Name	Application	Type
NS-029CN	Mouse Anti-GD2 Recombinant Antibody (clone 5F11)	WB	Mouse IgG
NS-030CN	Mouse Anti-GD2 Recombinant Antibody (clone 3G6)	WB	Mouse IgG
NS-029CN-F(E)	Mouse Anti-GD2 Recombinant Antibody (clone 5F11); Fab Fragment	WB	Mouse Fab
NS-030CN-F(E)	Mouse Anti-GD2 Recombinant Antibody (clone 3G6); Fab Fragment	WB	Mouse Fab
NS-029CN-S(P)	Mouse Anti-GD2 Recombinant Antibody (clone 5F11); scFv Fragment	WB	Mouse scFv

scFv Fragment Antibody

CAT	Product Name	Application	Type
FAMAB-0126-YC-S(P)	Mouse Anti-GD2 Recombinant Antibody (clone 7A4); scFv Fragment	ELISA	Mouse scFv
HPAB-0027-WJ-S(P)	Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-0027-WJ-S(P))	ELISA, RIA	Mouse scFv
HPAB-1030WJ-S(P)	Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-1030WJ-S(P))	ELISA	Mouse scFv
HPAB-1524WJ-S(P)	Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM8138)	ELISA, WB	Human scFv
HPAB-1525WJ-S(P)	Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM1138)	ELISA, WB	Human scFv

ADCC Enhanced Antibody

CAT	Product Name	Application	Type
AFC-TAB-731	Afuco™ Anti-GD2 ADCC Recombinant Antibody (Dinutuximab), ADCC Enhanced	Neut, ELISA, IF, IP, FuncS, FC	ADCC enhanced antibody

Customer Reviews and Q&As

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-GD2 Recombinant Antibody (Dinutuximab) (CAT#: TAB-731)