Anti-GD2 Recombinant Antibody (Dinutuximab) (CAT#: TAB-731)

Recombinant chimeric (human/Mouse) antibody expressed in CHO binding to human GD2. Dinutuximab is a chimeric monoclonal antibody that induces antibody dependent cell-mediated cytotoxicity. Dinutuximab is intended as maintenance therapy (targeting minimal residual disease) for high risk neuroblastoma, administered after induction therapy, autologous stem cell transplantation and/or radiotherapy.

Host: Mouse

Isotype: IgG1 - kappa

Applications: Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.


Specific Inquiry
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  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Chimeric (Human/Mouse)
  • Type
  • IgG1 - kappa
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
  • Trade name
  • Unituxin
  • Generic Name
  • dinutuximab
  • Related Disease
  • Neuroblastoma

Product Property

  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • dinutuximab;Unituxin;Ch14.18;APN311;Disialoganglioside GD2;Ganglioside G2;GD2

Related Resources

  • Biosimilar Overview
Please refer to Dinutuximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Dinutuximab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Dinutuximab"

Afuco™ Anti-GD2 ADCC Recombinant Antibody (Dinutuximab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant chimeric (human/Mouse) antibody expressed in CHO binding to human GD2. Dinutuximab is a chimeric monoclonal antibody that induces antibody dependent cell-mediated cytotoxicity. Dinutuximab is intended as maintenance therapy (targeting minimal residual disease) for high risk neuroblastoma, administered after induction therapy, autologous stem cell transplantation and/or radiotherapy.

See other products for "GD2"

Single-domain Antibody

CAT Product Name Application Type
NAB-770-sdAb Recombinant Anti-Human GD2 VHH Single Domain Antibody Neut, ChiP, IP, FUNC Llama VHH

Immunotoxin

CAT Product Name Application Type
AGTO-L018R anti-GD2 immunotoxin 14G2a (IgG)-RTA Cytotoxicity assay, Functional assay

Humanized Antibody

CAT Product Name Application Type
TAB-304CL Anti-Human GD2 Recombinant Antibody (hu14.18K322A) FC, FuncS Antibody
PABX-059 Human Anti-GD2 Recombinant Antibody (PABX-059) FuncS IgG1, κ
PABX-059-F (E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (PABX-059-F (E)) FC, ELISA, FuncS Human Fab

Recombinant Antibody

CAT Product Name Application Type
PABL-100 Mouse Anti-GD2 Recombinant Antibody (clone 14G2a) ELISA, WB, FuncS Mouse IgG
FAMAB-0126YC Mouse Anti-GD2 Recombinant Antibody (clone 7A4) ELISA Mouse IgG3, κ
HPAB-0701-CN Human Anti-GD2 Recombinant Antibody (clone AB527) ELISA, FC, IHC, IF Human IgM
HPAB-0027-WJ Mouse Anti-GD2 Recombinant Antibody (HPAB-0027-WJ) ELISA, RIA Mouse IgG3, κ
HPAB-1030WJ Human Anti-GD2 Recombinant Antibody (HPAB-1030WJ) ELISA Chimeric (mouse/human) IgG

Fab Fragment Antibody

CAT Product Name Application Type
PFBL-100 Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); Fab Fragment ELISA, WB, FuncS Mouse Fab
PFBL-101 Mouse Anti-GD2 Recombinant Antibody (clone 3F8); Fab Fragment FC, ELISA, FuncS Mouse Fab
PFBZ-049 Mouse Anti-GD2 Recombinant Antibody (clone ME36.1); Fab Fragment WB, FuncS Mouse Fab
HPAB-1524WJ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM8138) ELISA, WB Human Fab
HPAB-1525WJ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (clone KM1138) ELISA, WB Human Fab

Human Antibody

CAT Product Name Application Type
TAB-074CQ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-074CQ-F(E)) ELISA, FC Human Fab
TAB-075CQ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-075CQ-F(E)) ELISA, FC Human Fab
TAB-076CQ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-076CQ-F(E)) ELISA, FC Human Fab
TAB-077CQ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-077CQ-F(E)) ELISA, FC Human Fab
TAB-078CQ-F(E) Human Anti-GD2 Recombinant Antibody; Fab Fragment (TAB-078CQ-F(E)) ELISA, FC Human Fab

Neuroscience Antibody

CAT Product Name Application Type
NS-029CN Mouse Anti-GD2 Recombinant Antibody (clone 5F11) WB Mouse IgG
NS-030CN Mouse Anti-GD2 Recombinant Antibody (clone 3G6) WB Mouse IgG
NS-029CN-F(E) Mouse Anti-GD2 Recombinant Antibody (clone 5F11); Fab Fragment WB Mouse Fab
NS-030CN-F(E) Mouse Anti-GD2 Recombinant Antibody (clone 3G6); Fab Fragment WB Mouse Fab
NS-029CN-S(P) Mouse Anti-GD2 Recombinant Antibody (clone 5F11); scFv Fragment WB Mouse scFv

scFv Fragment Antibody

CAT Product Name Application Type
FAMAB-0126-YC-S(P) Mouse Anti-GD2 Recombinant Antibody (clone 7A4); scFv Fragment ELISA Mouse scFv
HPAB-0027-WJ-S(P) Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-0027-WJ-S(P)) ELISA, RIA Mouse scFv
HPAB-1030WJ-S(P) Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-1030WJ-S(P)) ELISA Mouse scFv
HPAB-1524WJ-S(P) Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM8138) ELISA, WB Human scFv
HPAB-1525WJ-S(P) Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM1138) ELISA, WB Human scFv

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-731 Afuco™ Anti-GD2 ADCC Recombinant Antibody (Dinutuximab), ADCC Enhanced Neut, ELISA, IF, IP, FuncS, FC ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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