Anti-Human BLys Recombinant Antibody (Belimumab) (CAT#: TAB-030)

Recombinant monoclonal antibody to Human BLyS. Belimumab (trade name Benlysta, previously known as LymphoStat-B) is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS). B cells are responsible for part of the normal immune response, and also for the over-aggressive immune response in autoimmune diseases like systemic lupus erythematosus (SLE).

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SDS-PAGE

Figure 1 Anti-Human BLys Recombinant Antibody (TAB-030) in SDS-PAGE

SDS-PAGE analysis of TAB-030 in non-reduced (Lane 1) and reduced (Lane 2) conditions.

SEC-HPLC

Figure 2 Anti-Human BLys Recombinant Antibody (TAB-030) in HPLC

HPLC analysis of TAB-030 shows the purity is>95%.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1 - lambda
  • Specificity
  • Tested positive against native human antigen
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
  • Trade name
  • Benlysta
  • CAS
  • 356547-88-1
  • Generic Name
  • Belimumab
  • ATC Code
  • L04AA26
  • UNII
  • 73B0K5S26A
  • MW
  • 151.8 kDa
  • Related Disease
  • Systemic lupus erythematosus (SLE)

Target

  • Alternative Names
  • Belimumab;Benlysta;356547-88-1;HGS1006;Benlysta;LymphoStat-B;B-lymphocyte stimulator (BLyS);TNFSF13B;tumor necrosis factor (ligand) superfamily, member 13b;TNFSF20;tumor necrosis factor ligand superfamily member 13B;BAFF;BLYS;CD257;TALL 1;TALL1;THANK;delt

Related Resources

  • Biosimilar Overview
Please click here for more details about the introduction to mechanism of action, clinical projects and approved drugs of Belimumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Belimumab"

Afuco™ Anti-TNFSF13B ADCC Recombinant Antibody (Belimumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human BLyS. Belimumab (trade name Benlysta, previously known as LymphoStat-B) is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS). B cells are responsible for part of the normal immune response, and also for the over-aggressive immune response in autoimmune diseases like systemic lupus erythematosus (SLE).

See other products for "TNFSF13B"

Single-domain Antibody

CAT Product Name Application Type
NABG-024 Recombinant Anti-Human TNFSF13B VHH Single Domain Antibody CA, IP, IF, FuncS Llama VHH
TAB-0055CL-VHH Anti-Human TNFSF13B VHH Single Domain Antibody (BAFF52) ELISA, FuncS, Inhib, BLI Single domain antibody
HPAB-0235-YJ-VHH Recombinant Llama Anti-TNFSF13B Single Domain Antibody (CBT06YJ) ELISA, Inhib Llama VHH
HPAB-0236-YJ-VHH Recombinant Llama Anti-TNFSF13B Single Domain Antibody (G3) ELISA, Inhib Llama VHH
HPAB-0237-YJ-VHH Recombinant Llama Anti-TNFSF13B Single Domain Antibody (52) ELISA, Inhib Llama VHH

Chimeric Antibody

CAT Product Name Application Type
TAB-1179CL Human Anti-TNFSF13B Recombinant Antibody (TAB-1179CL) Neut Chimeric (Mouse/Human) antibody
TAB-1179CL-S(P) Human Anti-TNFSF13B Recombinant Antibody; scFv Fragment (TAB-1179CL-S(P)) Neut Human scFv
TAB-1180CL-S(P) Human Anti-TNFSF13B Recombinant Antibody; scFv Fragment (TAB-1180CL-S(P)) Neut Human scFv
TAB-1179CL-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1179CL-F(E)) Neut Chimeric (Mouse/Human) Fab
TAB-1180CL-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1180CL-F(E)) Neut Chimeric (Mouse/Human) Fab

Mouse Antibody

CAT Product Name Application Type
TAB-1181CL Anti-Human TNFSF13B Recombinant Antibody (H1104-30) ELISA, Inhib
TAB-1183CL Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1183CL) ELISA, Inhib Mouse IgG2b, κ
TAB-1184CL Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1184CL) ELISA, Inhib Mouse IgG2b, κ
TAB-1185CL Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1185CL) ELISA, Inhib Mouse IgG2a, κ
TAB-1157CL-F(E) Mouse Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1157CL-F(E)) ELISA, WB, FuncS Mouse Fab

Humanized Antibody

CAT Product Name Application Type
TAB-1194CL-S(P) Human Anti-TNFSF13B Recombinant Antibody; scFv Fragment (TAB-1194CL-S(P)) ELISA Human scFv
TAB-1194CL-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1194CL-F(E)) ELISA Humanized Fab
TAB-1195CL-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1195CL-F(E)) ELISA Humanized Fab
TAB-1196CL-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1196CL-F(E)) ELISA Humanized Fab
TAB-1197CL-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1197CL-F(E)) ELISA Humanized Fab

Human Antibody

CAT Product Name Application Type
TAB-1158CL-F(E) Anti-Human TNFSF13B Recombinant Antibody Fab Fragment (6C10) ELISA, Inhib Fully human antibody
TAB-1159CL-F(E) Anti-Human TNFSF13B Recombinant Antibody Fab Fragment (10C11) ELISA, Inhib Fully human antibody
TAB-1160CL-F(E) Anti-Human TNFSF13B Recombinant Antibody Fab Fragment (6A11) ELISA Fully human antibody
TAB-1161CL-F(E) Anti-Human TNFSF13B Recombinant Antibody Fab Fragment (5B7) ELISA, Inhib Fully human antibody
TAB-1162CL-F(E) Anti-Human TNFSF13B Recombinant Antibody Fab Fragment (1B7) ELISA, Inhib Fully human antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-2184CQ Rat Anti-TNFSF13B Recombinant Antibody (clone 8F10) Neut, FC, IHC, IHC-Fr Rat IgG2a
NEUT-2185CQ Mouse Anti-TNFSF13B Recombinant Antibody (clone CBL701) Neut Mouse IgG2b

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3973 Rabbit Anti-TNFSF13B Recombinant Antibody (clone SI33DS) WB, FC, IP Rabbit IgG
MOR-4470 Rabbit Anti-TNFSF13B Recombinant Antibody (clone SI564DS) FC Rabbit IgG
MOR-4471 Rabbit Anti-TNFSF13B Recombinant Antibody (clone SI565DS) ELISA Rabbit IgG
MOR-4537 Rabbit Anti-TNFSF13B Recombinant Antibody (clone TH45DS) WB Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0235-YC-S(P) Human Anti-TNFSF13B Recombinant Antibody; scFv Fragment (HPAB-0235-YC-S(P)) ELISA, Neut Human scFv
HPAB-0121-FY-S(P) Mouse Anti-TNFSF13B Recombinant Antibody; scFv Fragment (HPAB-0121-FY-S(P)) ELISA Mouse scFv
HPAB-1877LY-S(P) Human Anti-TNFSF13B Recombinant Antibody; scFv Fragment (HPAB-1877LY-S(P)) Inhib Human scfv
HPAB-1623-FY-F(E) Mouse Anti-TNFSF13B Recombinant Antibody (clone FMMU-BAFF-4); scFv Fragment ELISA, FC Mouse scFv
FAMAB-0324JF-S(P) Mouse Anti-TNFSF13B Recombinant Antibody (clone ABL-1); scFv Fragment WB, ELISA, FuncS Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0235-YC-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (HPAB-0235-YC-F(E)) ELISA, Neut Human Fab
HPAB-0121-FY-F(E) Mouse Anti-TNFSF13B Recombinant Antibody; Fab Fragment (HPAB-0121-FY-F(E)) ELISA Mouse Fab
HPAB-1877LY-F(E) Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (HPAB-1877LY-F(E)) Inhib Human Fab
HPAB-N0286-YC-F(E) Human Anti-TNFSF13B Recombinant Antibody (clone h8E7D9C7F5-1); Fab Fragment ELISA, FC, Inhib Human Fab
FAMAB-0324JF-F(E) Mouse Anti-TNFSF13B Recombinant Antibody (clone ABL-1); Fab Fragment WB, ELISA, FuncS Mouse Fab

Recombinant Antibody

CAT Product Name Application Type
HPAB-0730LY Human Anti-TNFSF13B Recombinant Antibody (clone CBL016) ELISA Human IgG1
FN-033CQ Mouse Anti-TNFSF13B Recombinant Antibody (clone ANC2H3) ELISA, FC, Block Mouse IgG1, κ
FN-060CQ Mouse Anti-Tnfsf13b Recombinant Antibody (clone Sandy-2) FuncS, IP Mouse IgG1
HPAB-1877LY Human Anti-TNFSF13B Recombinant Antibody (HPAB-1877LY) Inhib Human IgG
HPAB-1623-FY Mouse Anti-TNFSF13B Recombinant Antibody (clone FMMU-BAFF-4) ELISA, FC Mouse IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-030 Afuco™ Anti-TNFSF13B ADCC Recombinant Antibody (Belimumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-216 Afuco™ Anti-TNFSF13B ADCC Recombinant Antibody (Tabalumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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