Anti-Human SOST Recombinant Antibody (TAB-115) (CAT#: TAB-115)
Recombinant monoclonal antibody to SOST. It binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Group enriched (HaCaT, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG4 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- FuncS, IF, Neut, ELISA, FC, IP, ICC, IO
- MW
- 144.63 kDa
- Related Disease
- Postmenopausal women osteoporosis
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Applications
- Application Notes
- The SOST antibody has been reported in applications of FuncS, IF, Neut, ELISA, FC, IP, ICC, IO.
Target
- Alternative Names
- Blosozumab;1132758-87-2;LY2541546;SOST;sclerostin;sclerosteosis;VBCH;
- Gene ID
- 50964
- UniProt ID
- Q9BQB4
Related Resources
Please refer to Blosozumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Blosozumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-116 | Human Anti-SOST Recombinant Antibody (TAB-116) | IF, IP, Neut, FuncS, ELISA, FC, ICC | Human IgG2, κ |
| TAB-580CL | Human Anti-SOST Recombinant Antibody (TAB-580CL) | ELISA, WB | Human IgG |
| TAB-411CT-S(P) | Humanized Anti-SOST Recombinant Antibody; scFv Fragment (TAB-411CT-S(P)) | ELISA, Neut | Humanized scFv |
| TAB-412CT-S(P) | Humanized Anti-SOST Recombinant Antibody; scFv Fragment (TAB-412CT-S(P)) | ELISA, Neut | Humanized scFv |
| TAB-413CT-S(P) | Humanized Anti-SOST Recombinant Antibody; scFv Fragment (TAB-413CT-S(P)) | ELISA, Neut | Humanized scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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