Recombinant Mouse anti-Human TGFB1 Monoclonal antibody (3D6)

Name: Recombinant Mouse anti-Human TGFB1 Monoclonal antibody (3D6)
SKU: MOB-2018CT
Rating: 5 (1 reviews)

CAT#: MOB-2018CT

Recombinant Mouse monoclonal antibody to Human TGFB1, expressed in Chinese Hamster Ovary cells(CHO).

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1901_C17_1_selected.jpg

Subcellular Location and Protein Expression Figure 2 IHC staining of human bone marrow

Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/ihc_selected.jpg

Subcellular Location and Protein Expression Figure 3 IF staining of human cell line HEL

Immunofluorescent staining of human cell line HEL shows localization to Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1812_G3_5_cr5a09c41109818_blue_red_green.jpg

Normal Tissue Figure 4 Bone marrow

Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/2675_B_6_4.jpg

RNA Expression Figure 5 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105329-TGFB1

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Specifications

Immunogen
The immunogen is TGF beta 1 isolated from human platelets.

Host Species
Mouse

Antibody Isotype
IgG1

Specificity
Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa.) forms of TGF beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinan

Species Reactivity
Human

Clone
3D6

Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Western Blot

Conjugate
Unconjugated

Product Property

Purity
Protein G purified

Format
Liquid

Concentration
1.0 mg/ml

Buffer
Preservative: None Constituents: 0.01M PBS, pH 7.2

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Alternative Names
TGFB1; transforming growth factor, beta 1; CED; LAP; DPD1; TGFB; TGFbeta; transforming growth factor beta-1; TGF-beta-1; latency-associated peptide; prepro-transforming growth factor beta-1;

Gene ID
7040

UniProt ID
P01137

Protein Refseq
NP_000651

Function
growth factor activity; protein N-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding

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Related Diseases

Inflammatory Bowel Diseases

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-2018CT.pdf

MSDS

MSDS - MOB-2018CT.pdf

COA

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