Recombinant Mouse anti-Human TGFB1 Monoclonal antibody (3D6)

Name: Recombinant Mouse anti-Human TGFB1 Monoclonal antibody (3D6)
SKU: MOB-2018CT
Rating: 5 (1 reviews)

CAT#: MOB-2018CT

Recombinant Mouse monoclonal antibody to Human TGFB1, expressed in Chinese Hamster Ovary cells(CHO).

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1901_C17_1_selected.jpg

Subcellular Location and Protein Expression Figure 2 IHC staining of human bone marrow

Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/ihc_selected.jpg

Subcellular Location and Protein Expression Figure 3 IF staining of human cell line HEL

Immunofluorescent staining of human cell line HEL shows localization to Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1812_G3_5_cr5a09c41109818_blue_red_green.jpg

Normal Tissue Figure 4 Bone marrow

Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/2675_B_6_4.jpg

RNA Expression Figure 5 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105329-TGFB1

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Specifications

Immunogen
TGF beta 1 from human platelets.

Host Species
Mouse

Specificity
Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa.) forms of TGF beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinan

Species Reactivity
Human

Clone
3D6

Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Western Blot

Conjugate
Unconjugated

Product Property

Purity
Protein G purified

Format
Liquid

Concentration
1.0 mg/ml

Buffer
Preservative: None Constituents: 0.01M PBS, pH 7.2

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Alternative Names
TGFB1; transforming growth factor, beta 1; CED; LAP; DPD1; TGFB; TGFbeta; transforming growth factor beta-1; TGF-beta-1; latency-associated peptide; prepro-transforming growth factor beta-1;

Gene ID
7040

UniProt ID
P01137

Protein Refseq
NP_000651

Function
growth factor activity; protein N-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding

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Related Diseases

Inflammatory Bowel Diseases

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MOB-2018CT.pdf

MSDS

MSDS - MOB-2018CT.pdf

COA

Certificate of Analysis Lookup

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