Recombinant Anti-TGFB1 Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC230)

• Host Animal 1
• Human

• Host Animal 2
• Human

• Specificity
• Human TGFB1

• Species Reactivity
• Human

• Type
• Tandem scFv

• Valency
• 1 + 1

• Epitope 1
• The helix3 region (Q67 and H68 are key residues)

• Epitope 2
• aa 83-112 of TGFβ1

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA, FC, ICC, IF, IP, Neut

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Transforming Growth Factor Beta 1

• Introduction
• On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

• Alternative Names
• TGFB1; transforming growth factor, beta 1; DPD1, TGFB; transforming growth factor beta-1; Camurati Engelmann disease; CED; TGFbeta; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide; LAP; DPD1; TGFB;

• Gene ID
• 7040

• UniProt ID
• P01137

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