Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody Fab Fragment (chSK48-E26) (CAT#: TAB-237CT-F(E))
Recombinant monoclonal antibody to interleukin 1 beta. chSK48-E26 is a chimeric(human/mouse) antibody intended for the prophylaxis and treatment of inflammatory disease.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Specifications
- Host Species
- Human
- Type
- Chimeric antibody (mouse/human)
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- chSK48-E26
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Neutralization
- Related Disease
- Inflammatory disease
Target
- Alternative Names
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
- Gene ID
- 3553
- UniProt ID
- P01584
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-239 | Human Anti-IL1B Recombinant Antibody (clone YC129) | WB, IHC, FuncS | Human IgG |
| PABL-608 | Human Anti-IL1B Recombinant Antibody (clone ACZ885) | Neut | Human IgG |
| HPAB-0682-WJ | Human Anti-IL1B Recombinant Antibody (clone E26) | ELISA | Humanized IgG |
| HPAB-0683-WJ | Human Anti-IL1B Recombinant Antibody (clone E26.1) | ELISA | Humanized IgG |
| HPAB-0684-WJ | Human Anti-IL1B Recombinant Antibody (clone E26.13-SS-X3) | ELISA | Humanized IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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