Human Anti-IL1B Recombinant Antibody (clone AAL160); Fab Fragment (CAT#: HPAB-0032-YC-F(E))
Interleukin I (IL-1) is an activity produced by cells of the immune system which acts as a mediator of the acute phase inflammatory response. Inappropriate or excessive production of IL-1, in particular IL-1β, is associated with the pathology of various diseases and disorders. such as septicemia, septic or endotoxic shock, allergies, asthma, bone loss, ischemia, stroke, rheumatoid arthrititis and other inflammatory disorders. Antibodies to IL-1β have been proposed for use in the treatment of IL-1 mediated diseases and disorders.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Specifications
- Immunogen
- Recombinant human IL-1β
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human IL1B
- Species Reactivity
- Human
- Clone
- AAL160
- Applications
- Neut, Block
- Related Disease
- Osteoarthritis, Osteroporosis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Rheumatoid Arthritis
Maturity Onset Diabetes of the Young
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-021 | Anti-Human IL1Beta Recombinant Antibody (Canakinumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
| TAB-545LC | Human Anti-IL1B Recombinant Antibody (TAB-545LC) | ELISA, Inhib, Neut | Human IgG1 |
| TAB-546LC | Human Anti-IL1B Recombinant Antibody (TAB-546LC) | ELISA, FC, Neut | Human IgG1 |
| TAB-545LC-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (TAB-545LC-F(E)) | ELISA, FC | Human Fab |
| TAB-546LC-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (TAB-546LC-F(E)) | ELISA, FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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