Can this antibody neutralize IL-1 beta activity?

Yes, the Rat Anti-Il1b Recombinant Antibody (clone CBL448) binds specifically to mouse IL-1 beta and is validated for neutralizing its bioactivity in functional assays.

Does this antibody contain preservatives?

No, this antibody is supplied in PBS without preservatives. This makes it ideal for use in live cell assays or functional studies where preservatives might be cytotoxic.

Rat Anti-Il1b Recombinant Antibody (clone CBL448)

CAT#: NEUT-1287CQ

This antibody is a rat monoclonal antibody that binds specifically to mouse IL-1 beta, and it can neutralize the bioactivity of mouse IL-1 beta.

Gene Expression

RNA Expression Figure 1 RNA cell line category: Cell line enhanced.

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B

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Specifications

Immunogen
Recombinant mouse IL-1 beta /IL-1F2

Host Species
Rat

Type
Rat IgG1

Specificity
Mouse Il1b

Species Reactivity
Mouse

Clone
CBL448

Applications
ELISA, Neut

Conjugate
Unconjugated

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Il1b; interleukin 1 beta; Il-1b; IL-1beta; IL-1F2; Il1b

Gene ID
16176

UniProt ID
P10749

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Breast cancer biomarkers at key points during disease progression

Potent Neutralizing Antibody

We used this rat monoclonal antibody to neutralize mouse IL-1 beta in our inflammatory response models. It was very effective and specifically bound to the cytokine without interfering with other factors. The recombinant production ensures high purity, which is essential for our sensitive bioassays.

Excellent ELISA Performance

This antibody (Clone CBL448) serves as a great capture antibody in our ELISA setup for mouse IL-1 beta. The binding is strong and specific. We appreciate that it is preservative-free, allowing us to use it in various functional setups without worrying about cytotoxicity.

Q&As

Can this antibody neutralize IL-1 beta activity?

A: Yes, the Rat Anti-Il1b Recombinant Antibody (clone CBL448) binds specifically to mouse IL-1 beta and is validated for neutralizing its bioactivity in functional assays.
Does this antibody contain preservatives?

A: No, this antibody is supplied in PBS without preservatives. This makes it ideal for use in live cell assays or functional studies where preservatives might be cytotoxic.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - NEUT-1287CQ.pdf

MSDS

MSDS - NEUT-1287CQ.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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