Recombinant Anti-human TEK Intrabody [(D-Arg)9]

CAT#: IAB-B064(A)

Recombinant anti-TEK intrabody linked to (D-Arg)9 works within cells to bind human TEK, expressed in E. coli cells.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IHC staining of human testis Figure 3 IF staining of human cell line AF22 Figure 4 IF staining of human cell line BJ Figure 5 Colon Figure 6 Testis Figure 7 RNA cell line category: Group enriched (HUVEC TERT2, NTERA-2, TIME) Figure 7 RNA cell line category: Group enriched (HUVEC TERT2, NTERA-2, TIME)

Specifications

  • Immunogen
  • human TEK tyrosine kinase, endothelial
  • Host Species
  • human
  • Type
  • scFv-(D-Arg)9
  • Cell Penetrating Peptide
  • (D-Arg)9
    It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
  • Species Reactivity
  • human
  • Applications
  • Formats of immunological tests: Protein fragment complementation; Neutralization; Functional studies

Product Property

  • Purity
  • >90% assessed by SDS-PAGE
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Target

  • Alternative Names
  • TEK; TEK tyrosine kinase, endothelial; TIE2; VMCM; TIE-2; VMCM1; CD202B; angiopoietin-1 receptor; endothelial tyrosine kinase; tyrosine-protein kinase receptor TEK; tunica interna endothelial cell kinase; tyrosine-protein kinase receptor TIE-2; tyrosine k
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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