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TEK

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This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Species Reactivity:
Human
Type:
Antibody
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
VELOCIMMUNE® mouse
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
VELOCIMMUNE® mouse
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
VELOCIMMUNE® mouse
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Species Reactivity:
Human
Type:
Mouse antibody
Application:
ELISA, FC, IHC-Fr, WB
Species Reactivity:
Zebrafish
Type:
IgG1
Application:
BL, WB
Species Reactivity:
Human
Type:
Mouse IgG
Application:
ELISA, Agonist
Species Reactivity:
Human
Type:
Mouse IgG
Application:
ELISA, Agonist
Species Reactivity:
Human
Type:
Mouse scFv
Application:
ELISA, Agonist
Species Reactivity:
Human
Type:
Mouse scFv
Application:
ELISA, Agonist
Species Reactivity:
Human
Type:
Mouse Fab
Application:
ELISA, Agonist
Species Reactivity:
Human
Type:
Mouse Fab
Application:
ELISA, Agonist
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
VELOCIMMUNE® mouse
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
VELOCIMMUNE® mouse
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
VELOCIMMUNE® mouse
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Species Reactivity:
Human
Type:
Fab
Application:
ELISA
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
WB, ICC/IF
Species Reactivity:
human
Type:
scFv-(D-Arg)9
Application:
PCA, Neut, FuncS
Species Reactivity:
human
Type:
scFv-(+36GFP)
Application:
WB, Neut, FuncS
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