Recombinant Mouse Anti-TEK Antibody (12H8)
CAT#: HPAB-0066-YJ
This product is a recombinant mouse monoclonal antibody that recognizes human TIE2. Mab reacts with the extracellular domain of TIE2 and functions as signal transduction modulators, angiopoietin-1 receptor (TEK, hTIE2) inhibitors, angiogenesis inhibitors. It is useful in Atherosclerosis Therapy and Oncolytic Drugs.
Tested Data
Gene Expression
SDS-PAGE
Figure 1 Anti-TEK Antibody (HPAB-0066-YJ) in SDS-PAGE
SDS-PAGE analysis of HPAB-0066-YJ in non-reduced (Lane 1) and β-mercaptoethanol-reduced (Lane 2) conditions.
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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & centriolar satellites.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73265/1607_D9_2_selected.jpg
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Specifications
- Immunogen
- Mice (Fl hybrids of Balb/c and C57BL/6) were immunised subcutaneously with recombinant Tie2 extracellular domain-Fc fusion in RIBI adjuvant and boosted with the same.
- Host Species
- Mouse
- Type
- Mouse IgG, κ
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 12H8
- Applications
- Immunoassay, Western Blot
- Related Disease
- Atherosclerosis, Tumor
Target
- Alternative Names
- TEK Receptor Tyrosine Kinase; Tyrosine Kinase With Ig And EGF Homology Domains-2; Tunica Interna Endothelial Cell Kinase; Tyrosine-Protein Kinase Receptor TIE-2; Tyrosine-Protein Kinase Receptor TEK; TEK Tyrosine Kinase, Endothelial; Endothelial Tyrosine Kinase; EC 2.7.10.1; VMCM1; VMCM; TIE2; 12H8 MAb
- Gene ID
- 7010
- UniProt ID
- Q02763
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 12H8"
- CAT
- Product Name
See other products for "TEK"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1030 | Mouse Anti-TEK Recombinant Antibody (clone YC183); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0564-CN-F(E) | Mouse Anti-TEK Recombinant Antibody (clone 15B8); Fab Fragment | ELISA, Agonist | Mouse Fab |
| HPAB-0066-YJ-F(E) | Recombinant Mouse Anti-TEK Antibody Fab Fragment (12H8) | Immunoassay, WB | Mouse Fab |
| HPAB-S0139-YC-F(E) | Mouse Anti-TEK Recombinant Antibody (clone 12H8); Fab Fragment | ELISA, Antagonist | Mouse Fab |
| HPAB-S0140-YC-F(E) | Mouse Anti-TEK Recombinant Antibody (clone 6A3); Fab Fragment | ELISA, Antagonist | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B064(A) | Recombinant Anti-human TEK Intrabody [(D-Arg)9] | PCA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B064(G) | Recombinant Anti-human TEK Intrabody [+36 GFP] | WB, Neut, FuncS | scFv-(+36GFP) |
| IAB-B064(T) | Recombinant Anti-human TEK Intrabody [Tat] | ELISA, ICC, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-655CT | Human Anti-TEK Recombinant Antibody (TAB-655CT) | ELISA | Human IgG |
| TAB-656CT | Human Anti-TEK Recombinant Antibody (TAB-656CT) | ELISA | Human IgG |
| TAB-657CT | Human Anti-TEK Recombinant Antibody (TAB-657CT) | ELISA | Human IgG |
| TAB-658CT | Human Anti-TEK Recombinant Antibody (TAB-658CT) | ELISA | Human IgG |
| TAB-655CT-S(P) | Human Anti-TEK Recombinant Antibody; scFv Fragment (TAB-655CT-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0758MZ | Chicken Anti-TIE2 Polyclonal IgY | ELISA, IHC, IP, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1993CQ | Recombinant Mouse Anti-tek Antibody (CBL344) | BL, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3530 | Rabbit Anti-TEK Recombinant Antibody (clone DS3530AB) | WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0564-CN | Mouse Anti-TEK Recombinant Antibody (clone 15B8) | ELISA, Agonist | Mouse IgG |
| HPAB-0565-CN | Mouse Anti-TEK Recombinant Antibody (clone 13H10) | ELISA, Agonist | Mouse IgG |
| FN-254CQ | Rat Anti-TEK Recombinant Antibody (clone TEK4) | FC, FuncS, IHC-Fr | Rat IgG1, κ |
| HPAB-S0139-YC | Mouse Anti-TEK Recombinant Antibody (clone 12H8) | ELISA, Antagonist | Mouse IgG |
| HPAB-S0140-YC | Mouse Anti-TEK Recombinant Antibody (clone 6A3) | ELISA, Antagonist | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0418-WJ-S(P) | Human Anti-TEK Recombinant Antibody; scFv Fragment (HPAB-0418-WJ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0419-WJ-S(P) | Human Anti-TEK Recombinant Antibody; scFv Fragment (HPAB-0419-WJ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0420-WJ-S(P) | Human Anti-TEK Recombinant Antibody; scFv Fragment (HPAB-0420-WJ-S(P)) | ELISA, FC | Human scFv |
| HPAB-S0139-YC-S(P) | Mouse Anti-TEK Recombinant Antibody (clone 12H8); scFv Fragment | ELISA, Antagonist | Mouse scFv |
| HPAB-S0140-YC-S(P) | Mouse Anti-TEK Recombinant Antibody (clone 6A3); scFv Fragment | ELISA, Antagonist | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY76 | Mouse Anti-TEK (clone 12H8) scFv-Fc Chimera | Antagonist | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC649 | Recombinant Anti-TEK Vesicular Antibody, EV Displayed (VS-0425-YC649) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7167 | Anti-TEK Immunohistochemistry Kit | IHC |
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