Anti-Human TFPI Recombinant Antibody
CAT#: TAB-602CL
Recombinant Human monoclonal antibody expressed in CHO binding to Human TFPI. The monoclonal antibodiess that bind human tissue factor pathway inhibitor (TFPI) are used for treatment of genetic and acquired deficiencies or defects in coagulation such as hemophilia A and B.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human smooth muscle
Immunohistochemical staining of human smooth muscle shows distinct positivity in endothelial.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5575/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows distinct cytoplasmic positivity in endothelium.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells Staining: High Intensity: Strong Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25% Peripheral nerve/ganglion Staining: Low Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_7_3.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Decidual cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HHSteC, HUVEC TERT2, LHCN-M2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003436-TFPI
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Hemophilia
Product Property
- Purity
- 95% by HPLC
- Storage
- 4 °C, -20°C if preferred
Target
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Human TFPI Antibody
I needed a human recombinant antibody for my research on coagulation. This antibody, TAB-602CL, is specified as human and targets human TFPI. The CHO expression system is a plus for proper folding. This fits my requirements for an in vitro model studying the tissue factor pathway.
Good Specs for Research
The specifications for this antibody are clear. It's a human antibody targeting TFPI, which is exactly what our lab needs for studying its role in hemostasis. Being expressed in CHO cells gives us confidence in its structure and consistency. This is a promising reagent for our research.
Q&As
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What is the host and expression system for this anti-TFPI antibody?
A: This is a recombinant human antibody, which means its genetic origin is human. It is produced using our mammalian CHO (Chinese Hamster Ovary) cell expression system. This is a common system used in research to help ensure that human proteins, like this antibody, have relevant post-translational modifications.
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I'm studying the coagulation cascade. What is the target of this antibody, TAB-602CL?
A: This antibody targets human TFPI, or Tissue Factor Pathway Inhibitor. TFPI is a critical protein in hematology research, as it's a natural anticoagulant that regulates the extrinsic pathway of coagulation. This recombinant human antibody is designed for research use, reacting with the human form of TFPI.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3593z | Mouse Anti-TFPI Recombinant Antibody (clone 41B4) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-734 | Anti-TFPI Recombinant Antibody (Concizumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-718 | Human Anti-TFPI Recombinant Antibody (clone mAb 2021) | Block | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-711 | Human Anti-TFPI Recombinant Antibody (clone mAb 2021); Fab Fragment | Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-711 | Human Anti-TFPI Recombinant Antibody (clone mAb 2021); scFv Fragment | Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0374MZ | Recombinant Mouse Anti-Human Tissue Factor Pathway Inhibitor Antibody (clone BIUGQJ-5139) | RIA, WB, ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2015CT | Recombinant Mouse anti-Human TFPI Monoclonal antibody (5H5) | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3547 | Rabbit Anti-TFPI Recombinant Antibody (clone DS3547AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0476-CN | Mouse Anti-TFPI Recombinant Antibody (HPAB-0476-CN) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0476-CN-S(P) | Mouse Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0476-CN-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0477-CN-S(P) | Mouse Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0477-CN-S(P)) | ELISA, Neut | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0478-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0478-CN-S(P)) | ELISA, Neut | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0479-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0479-CN-S(P)) | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0476-CN-F(E) | Mouse Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0476-CN-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0477-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0477-CN-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0478-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0478-CN-F(E)) | ELISA, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0479-CN-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0479-CN-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-734 | Afuco™ Anti-TFPI ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-734) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC647 | AbPlus™ Anti-TFPI Magnetic Beads (VS-0724-YC647) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY189 | Human Anti-TFPI (clone Concizumab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7198 | Anti-TFPI Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC305 | Recombinant Anti-TFPI Eliminating Antibody, pH-Sensitive (VS-0625-YC305) | Antigen-Sweeping In Vivo. | Human IgG4 kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC323 | SmartAb™ Recombinant Anti-TFPI pH-dependent Antibody (VS-0825-YC323) | ELISA, FC, Neut | Mouse IgG1 kappa |
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