PE-A*68:02/Human TP53 (AAPPVAPA) MHC Tetramer
CAT#: MHC-LC3049
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TP53 of peptide AAPPVAPA covering 69-76 and A*68:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39239/651_G2_2_selected.jpg
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Specifications
- Allele
- A*68:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- TP53
- Antigen Species
- Human
- Peptide
- AAPPVAPA
- Range
- 69-76
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
- Alternative Names
- TP53; P53_HUMAN Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13); P53; BCC7; LFS1; TRP53
- Gene ID
- 7157
- UniProt ID
- P04637
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| CAT | Product Name | Application | Type |
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| PNBL-072 | Recombinant Anti-p53 VHH Single Domain Antibody (PNBL-072) | Inhib, IP, WB, ELISA, FuncS | Llama VHH |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3644 | Rabbit Anti-TP53 Recombinant Antibody (clone DS3644AB) | IHC-P | Rabbit IgG |
| MOR-4524 | Rabbit Anti-TP53 Recombinant Antibody (clone TH32DS) | WB, IF, ICC | Rabbit IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MD-ZBF-YC001 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-1.1) | WB, ICC | Mouse antibody |
| MD-ZBF-YC002 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-2.1) | WB, ICC, IHC | Mouse antibody |
| MD-ZBF-YC003 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-3.1) | WB, ICC | Mouse antibody |
| MD-ZBF-YC004 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-4.1) | WB, ICC | Mouse antibody |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); Fab Fragment | IHC, WB, ELISA | Mouse Fab |
| HPAB-0002-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 240); Fab Fragment | IP, ELISA | Mouse Fab |
| HPAB-0003-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 246); Fab Fragment | IP, ELISA | Mouse Fab |
| HPAB-0004-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 421); Fab Fragment | IP, ELISA | Mouse Fab |
| HPAB-1568WJ-F(E) | Mouse Anti-TP53 Recombinant Antibody; Fab Fragment (clone 11D3) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0633CQ | Mouse Anti-TP53 Recombinant Antibody (clone p53-11) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1045-CN | Rabbit Anti-TP53 Recombinant Antibody (clone JB42-26) | WB, IHC, FC, IP, IF | Rabbit IgG |
| MRO-2351-CN | Rabbit Anti-TP53 Recombinant Antibody (clone CBACN-640) | WB | Rabbit IgG |
| MRO-2352-CN | Rabbit Anti-TP53 Recombinant Antibody (clone CBACN-641) | WB | Rabbit IgG |
| HPAB-A1321-YJ | Human Anti-TP53 Recombinant Antibody (clone 163.17) | ELISA, IP | Human IgG1 |
| HPAB-A1322-YJ | Human Anti-TP53 Recombinant Antibody (clone 163.1) | ELISA, IP | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY261 | AbPlus™ Anti-TP53 Magnetic Beads (240) | IP, Protein Purification | |
| VS-0724-YC1290 | AbPlus™ Anti-TP53 Magnetic Beads (VS-0724-YC1290) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY361 | Mouse Anti-NHP TP53 Recombinant Antibody (clone BP53-12) | WB, IHC, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
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