Recombinant Anti-Human TNFRSF9 Antibody (Fc glycosylation/High-mannose glycosylated)

Name: Recombinant Anti-Human TNFRSF9 Antibody (Fc glycosylation/High-mannose glycosylated)
SKU: Gly-064LC
Rating: 5 (1 reviews)

CAT#: Gly-064LC

This product is a human monoclonal antibody with N-glycosylation site in the Fc region. The antibody with enhanced ADCC specifically binds human CD137 and can be potentially used in the treatment of autoimmune disease.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg

RNA Expression Figure 2 RNA cell line category: Cell line enriched (HDLM-2)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9

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Glyco-engineering

Glycosylation site
Fc region

Glycoform (ratio)
Man5 without fucose

Glycosylation Type
N-glycosylation

Activity
Enhanced ADCC

Specifications

Target
CD137 (Cluster of differentiation-137)

Host Species
Human

Type
Human antibody

Specificity
Human

Antibody Isotype
IgG

Expression Host
CHO

Applications
ELISA

Target

Alternative Names
TNFRSF9; tumor necrosis factor receptor superfamily, member 9; ILA; 4-1BB; CD137; CDw137; tumor necrosis factor receptor superfamily member 9; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor p

Related Disease
Autoimmune disease

Gene ID
3604

UniProt ID
Q07011

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Downloadable Resources

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Datasheet

Datasheet - Gly-064LC.pdf

MSDS

MSDS - Gly-064LC.pdf

COA

Certificate of Analysis Lookup

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