Recombinant Anti-Human TNFRSF9 Antibody (Fc glycosylation/High-mannose glycosylated) (CAT#: Gly-064LC)
This product is a human monoclonal antibody with N-glycosylation site in the Fc region. The antibody with enhanced ADCC specifically binds human CD137 and can be potentially used in the treatment of autoimmune disease.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9
Glyco-engineering
- Glycosylation site
- Fc region
- Glycoform (ratio)
- Man5 without fucose
- Glycosylation Type
- N-glycosylation
- Activity
- Enhanced ADCC
Specifications
- Target
- CD137 (Cluster of differentiation-137)
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Antibody Isotype
- IgG
- Expression Host
- CHO
- Applications
- ELISA
Target
- Alternative Names
- TNFRSF9; tumor necrosis factor receptor superfamily, member 9; ILA; 4-1BB; CD137; CDw137; tumor necrosis factor receptor superfamily member 9; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor p
- Related Disease
- Autoimmune disease
- Gene ID
- 3604
- UniProt ID
- Q07011
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-179 | Anti-Human 4-1BB Recombinant Antibody (TAB-179) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
| TAB-457CQ | Anti-Human TNFRSF9 Recombinant Antibody (TAB-457CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, λ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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