Recombinant Anti-TNFRSF9 Vesicular Antibody, EV Displayed (VS-0425-YC223)
CAT#: VS-0425-YC223
The Recombinant Anti-TNFRSF9 Vesicular Antibody, EV Displayed (VS-0425-YC223) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TNFRSF9-expressed cells or tissues. The TNFRSF9 is a receptor promoting T cell survival and proliferation, enhancing apoptosis under certain conditions. It interacts with TRAF adaptors.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TNFRSF9
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- TNF receptor superfamily member 9
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Nucleoli
- Introduction
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
- Alternative Names
- 4-1BB, CD137, ILA
- Gene ID
- 3604
- UniProt ID
- Q07011
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| TAB-0611CLV-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0611CLV-F(E)) | ELISA, FC | Humanized Fab |
| TAB-0612CLV-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0612CLV-F(E)) | ELISA | Humanized Fab |
| TAB-0611CLV-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0611CLV-S(P)) | ELISA, FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| TAB-0614CLV | Human Anti-TNFRSF9 Recombinant Antibody (TAB-0614CLV) | ELISA | Chimeric (mouse/human) IgG1 |
| TAB-0613CLV-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0613CLV-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-0613CLV-S(P) | Mouse Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0613CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0614CLV-S(P) | Mouse Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0614CLV-S(P)) | ELISA | Mouse scFv |
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|---|---|---|---|
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| HPAB-0053-FY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0053-FY) | ELISA | Human IgG2 |
| HPAB-0809LY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0809LY) | FC, FuncS | Human IgG1 |
| HPAB-0810LY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0810LY) | FC, FuncS | Human IgG1 |
| HPAB-0811LY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0811LY) | FC, FuncS | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| NEUT-2168CQ | Hamster Anti-Tnfrsf9 Recombinant Antibody (clone 17B5) | FC, Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2169CQ | Rat Anti-Tnfrsf9 Recombinant Antibody (NEUT-2169CQ) | Neut, WB | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0253-CN-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0253-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0254-CN-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0254-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0255-CN-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0255-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0256-CN-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0256-CN-S(P)) | FC | Human scFv |
| HPAB-0809LY-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0809LY-S(P)) | FC, FuncS | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0834LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0834LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0835LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0835LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0836LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0836LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0837LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0837LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0838LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0838LY-F(E)) | FC, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY51 | Rat Anti-Tnfrsf9 Agonistic Antibody (VS-0724-XY51) | Agonistic assays | Rat IgG2a |
| VS-0724-XY52 | Rabbit Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY52) | FC, Agonistic assays, CyTOF® | Rabbit IgG |
| VS-0724-XY53 | Human Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY53) | ELISA, Agonistic assays | Human IgG1 |
| VS-0724-XY54 | Rabbit Anti-TNFRSF9 Agonistic Antibody (clone RbBBK4) | ELISA, FC, Agonistic assays | Rabbit IgG, kappa |
| VS-0724-XY55 | Mouse Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY55) | ELISA, FC, Agonistic assays | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| VS-0225-XY225 | CytoStream™ Mouse Anti-TNFRSF9 Recombinant Antibody (VS-0225-XY225) | FC | Mouse IgG1, kappa |
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