Anti-Human 4-1BB Recombinant Antibody (TAB-179) (CAT#: TAB-179)

Recombinant monoclonal antibody to 4-1BB. This anti-4-1BB antibody is a fully human IgG4 monoclonal antibody targeting the CD137 receptor. It specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells.

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WB

Figure 1 Anti-Human 4-1BB Therapeutic Antibody (TAB-179) in WB

Figure 1 Anti-Human 4-1BB Therapeutic Antibody (TAB-179) in WB

Western blot analysis of TAB-179 was performed with Recombinant Human CD137 Protein (His Tag).
Lane 1: Reducing antigen (0.1μg)
Lane 2: Reducing antigen (0.3μg)
Lane 3: Reducing antigen (0.6μg)
The secondary antibody: HRP Goat Anti-Human IgG (H+L)

ELISA

Figure 2 Anti-Human 4-1BB Therapeutic Antibody (TAB-179) in ELISA

Figure 2 Anti-Human 4-1BB Therapeutic Antibody (TAB-179) in ELISA

ELISA analysis of TAB-179 was performed by coating with Recombinant Human CD137 Protein (His Tag).
The secondary antibody: HRP Goat Anti-Human IgG (H+L)

DB

Figure 2 Anti-Human 4-1BB Therapeutic Antibody (TAB-179) in Dot Blot

Figure 2 Anti-Human 4-1BB Therapeutic Antibody (TAB-179) in Dot Blot

Dot Blot analysis of TAB-179 was performed with Recombinant Human CD137 Protein (His Tag).
The secondary antibody: HRP Goat Anti-Human IgG (H+L)


Specifications

  • Immunogen
  • Ectodomain of human 4-1BB recombinant protein.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG4 - kappa
  • Specificity
  • Tested positive against native human antigen.
  • Species Reactivity
  • Human
  • Applications
  • ELISA, FC, IP, FuncS, IF, Neut, ICC
  • MW
  • 145.8 kDa
  • Related Disease
  • Tumors

Product Property

  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • At -20°C for one year.

Applications

  • Application Notes
  • The TNFRSF9 antibody has been reported in applications of H&E staining, Activ, Stim, IF.

Target

  • Alternative Names
  • ILA; 4-1BB; CD137; CDw137; IMD109

Related Resources

  • Biosimilar Overview
  • Citations
Please refer to Urelumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Urelumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Customer Reviews and Q&As

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  • Excellent for Immune Research
    The Anti-Human 4-1BB Therapeutic Antibody (Urelumab) has significantly improved our immune cell studies. The specificity and sensitivity are outstanding, providing clear and reproducible results. This antibody has become essential for our research, enhancing the accuracy and reliability of our assays.
  • Effective in Flow Cytometry
    We incorporated this antibody into our flow cytometry experiments, and it's been a great asset. The specificity for 4-1BB is precise, allowing for accurate cell population analysis. The reliable performance has made it an invaluable tool in our lab.
  • Consistent and Reliable
    This antibody has proven to be consistent and reliable in our immunoassays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for 4-1BB have been particularly beneficial.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-179, RRID: AB_3111852)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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