Human Anti-TNFRSF9 (clone 39E3) scFv-Fc Chimera

Name: Human Anti-TNFRSF9 (clone 39E3) scFv-Fc Chimera
SKU: VS-0325-FY100
Rating: 5 (1 reviews)

CAT#: VS-0325-FY100

The anti-CD137 scFv-Fc antibody targets CD137 (4-1BB), a co-stimulatory molecule involved in immune cell activation. It has potential therapeutic applications in cancer immunotherapy and autoimmune diseases. The scFv-Fc format provides extended half-life and enhanced binding affinity, improving its therapeutic potential.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg

RNA Expression Figure 2 RNA cell line category: Cell line enriched (HDLM-2)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9

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Specifications

Host Species
Human

Type
Human IgG1, scFv-Fc

Specificity
39E3 is a human monoclonal antibody specific for human 4-1BB.

Species Reactivity
Human

Clone
39E3

Applications
Flow Cytometry

Related Disease
Cancer, autoimmune disease

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Ice packs

Target

Alternative Names
TNF Receptor Superfamily Member 9; T-Cell Antigen 4-1BB Homolog; 4-1BB Ligand Receptor; CD137 Antigen; CDw137; CD137; ILA; Interleukin-Activated Receptor, Homolog Of Mouse Ly63; Tumor Necrosis Factor Receptor Superfamily, Member 9

Gene ID
3604

UniProt ID
Q07011

Long Name
TNF Receptor Superfamily Member 9

Cellular Localization
Membrane

Protein Refseq
NP_001552.2

Function
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0325-FY100.pdf

MSDS

MSDS - VS-0325-FY100.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Isotype Control

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Secondary Antibody

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See other products for "TNFRSF9"

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TAB-0611CLV-S(P)	Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0611CLV-S(P))	ELISA, FC	Humanized scFv
TAB-0612CLV-S(P)	Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0612CLV-S(P))	ELISA	Humanized scFv

CAT	Product Name	Application	Type
TAB-0613CLV	Human Anti-TNFRSF9 Recombinant Antibody (TAB-0613CLV)	ELISA	Chimeric (mouse/human) IgG1
TAB-0614CLV	Human Anti-TNFRSF9 Recombinant Antibody (TAB-0614CLV)	ELISA	Chimeric (mouse/human) IgG1
TAB-0613CLV-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0613CLV-F(E))	ELISA	Chimeric (mouse/human) Fab
TAB-0613CLV-S(P)	Mouse Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0613CLV-S(P))	ELISA	Mouse scFv
TAB-0614CLV-S(P)	Mouse Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0614CLV-S(P))	ELISA	Mouse scFv

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NEUT-2167CQ	Rat Anti-Tnfrsf9 Recombinant Antibody (clone CBL332)	Block, WB	Rat IgG2b
NEUT-2168CQ	Hamster Anti-Tnfrsf9 Recombinant Antibody (clone 17B5)	FC, Block	Hamster IgG

CAT	Product Name	Application	Type
NEUT-2169CQ	Rat Anti-Tnfrsf9 Recombinant Antibody (NEUT-2169CQ)	Neut, WB	Rat IgG2

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HPAB-0253-CN-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0253-CN-F(E))	ELISA, FC	Human Fab
HPAB-0254-CN-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0254-CN-F(E))	ELISA, FC	Human Fab
HPAB-0255-CN-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0255-CN-F(E))	ELISA, FC	Human Fab
HPAB-0256-CN-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0256-CN-F(E))	FC	Human Fab
HPAB-0257-CN-F(E)	Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0257-CN-F(E))	FC	Human Fab

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HPAB-N0400-YC-S(P)	Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-N0400-YC-S(P))	ELISA, FC	Human scFv
HPAB-N0401-YC-S(P)	Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-N0401-YC-S(P))	ELISA, FC	Human scFv
HPAB-N0402-YC-S(P)	Mouse Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-N0402-YC-S(P))	FuncS	Mouse scFv
HPAB-N0403-YC-S(P)	Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-N0403-YC-S(P))	FuncS	Human scFv
HPAB-0809LY-S(P)	Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0809LY-S(P))	FC, FuncS	Human scfv

CAT	Product Name	Application	Type
HPAB-0809LY	Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0809LY)	FC, FuncS	Human IgG1
HPAB-0810LY	Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0810LY)	FC, FuncS	Human IgG1
HPAB-0811LY	Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0811LY)	FC, FuncS	Human IgG1
HPAB-0812LY	Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0812LY)	FC, FuncS	Human IgG1
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VS-0724-XY51	Rat Anti-Tnfrsf9 Agonistic Antibody (VS-0724-XY51)	Agonistic assays	Rat IgG2a
VS-0724-XY52	Rabbit Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY52)	FC, Agonistic assays, CyTOF®	Rabbit IgG
VS-0724-XY53	Human Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY53)	ELISA, Agonistic assays	Human IgG1
VS-0724-XY54	Rabbit Anti-TNFRSF9 Agonistic Antibody (clone RbBBK4)	ELISA, FC, Agonistic assays	Rabbit IgG, kappa
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VS-1024-XY76	Mouse Anti-NHP TNFRSF9 Recombinant Antibody (VS-1024-XY76)	FC	Mouse IgG1, kappa

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VS-0225-XY224	CytoStream™ Rat Anti-TNFRSF9 Recombinant Antibody (VS-0225-XY224)	FC	Rat IgG1, kappa
VS-0225-XY225	CytoStream™ Mouse Anti-TNFRSF9 Recombinant Antibody (VS-0225-XY225)	FC	Mouse IgG1, kappa

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VS-0425-YC223	Recombinant Anti-TNFRSF9 Vesicular Antibody, EV Displayed (VS-0425-YC223)	ELISA, FC, Neut, Cell-uptake

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