Human Anti-TNFRSF9 (clone 39E3) scFv-Fc Chimera (CAT#: VS-0325-FY100)
The anti-CD137 scFv-Fc antibody targets CD137 (4-1BB), a co-stimulatory molecule involved in immune cell activation. It has potential therapeutic applications in cancer immunotherapy and autoimmune diseases. The scFv-Fc format provides extended half-life and enhanced binding affinity, improving its therapeutic potential.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- 39E3 is a human monoclonal antibody specific for human 4-1BB.
- Species Reactivity
- Human
- Clone
- 39E3
- Applications
- Flow Cytometry
- Related Disease
- Cancer, autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- TNF Receptor Superfamily Member 9; T-Cell Antigen 4-1BB Homolog; 4-1BB Ligand Receptor; CD137 Antigen; CDw137; CD137; ILA; Interleukin-Activated Receptor, Homolog Of Mouse Ly63; Tumor Necrosis Factor Receptor Superfamily, Member 9
- Gene ID
- 3604
- UniProt ID
- Q07011
- Long Name
- TNF Receptor Superfamily Member 9
- Cellular Localization
- Membrane
- Protein Refseq
- NP_001552.2
- Function
- Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 39E3"
See other products for "TNFRSF9"
Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products
Immunotoxin Products
Fc Glycosylation Antibody Products
High-mannose Glycoform Antibody Products
Humanized Antibody Products
Chimeric Antibody Products
Blocking Antibody Products
Neutralizing Antibody Products
Fab Antibody Products
IgG Antibody Products
ScFv Antibody Products
ADCC Enhanced Antibody Products
Agonistic Antibody Products
Non-Human Primate (NHP) Antibody Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-179 | Anti-Human 4-1BB Recombinant Antibody (TAB-179) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
| TAB-457CQ | Anti-Human TNFRSF9 Recombinant Antibody (TAB-457CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, λ |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0325-FY100. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
-2-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, Neut
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
