Human Anti-TNFRSF9 (clone 39E3) scFv-Fc Chimera

CAT#: VS-0325-FY100

The anti-CD137 scFv-Fc antibody targets CD137 (4-1BB), a co-stimulatory molecule involved in immune cell activation. It has potential therapeutic applications in cancer immunotherapy and autoimmune diseases. The scFv-Fc format provides extended half-life and enhanced binding affinity, improving its therapeutic potential.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 RNA cell line category: Cell line enriched (HDLM-2)

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • 39E3 is a human monoclonal antibody specific for human 4-1BB.
  • Species Reactivity
  • Human
  • Clone
  • 39E3
  • Applications
  • Flow Cytometry
  • Related Disease
  • Cancer, autoimmune disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • TNF Receptor Superfamily Member 9; T-Cell Antigen 4-1BB Homolog; 4-1BB Ligand Receptor; CD137 Antigen; CDw137; CD137; ILA; Interleukin-Activated Receptor, Homolog Of Mouse Ly63; Tumor Necrosis Factor Receptor Superfamily, Member 9
  • Long Name
  • TNF Receptor Superfamily Member 9
  • Cellular Localization
  • Membrane
  • Function
  • Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Isotype Control

Secondary Antibody

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