Afuco™ Anti-TNFRSF9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-179)
CAT#: AFC-TAB-179
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to 4-1BB. It is a fully human IgG4 monoclonal antibody for the treatment of cancer and solid tumors.
targets the CD137 receptor. It specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71425/1522_F4_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000049249-TNFRSF9
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Specifications
- Immunogen
- Ectodomain of human 4-1BB recombinant protein.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Generic Name
- Urelumab
- Related Disease
- Tumors
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Urelumab"
DrugMonitor™ Anti-Urelumab Antibody (VS-1224-YC1266)Urelumab is a fully human antibody targeting CD137, studied in trials for leukemia, multiple myeloma, solid tumors, and B-cell non-Hodgkin's lymphoma. The DrugMonitor™ Anti-Urelumab Antibody (VS-1224-YC1266) is an anti-drug antibody (ADA) against Urelumab. This drug-based antibody is raised in mice immunized with the Urelumab. The anti-Urelumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Urelumab in samples.
See other products for "TNFRSF9"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-179 | Anti-Human 4-1BB Recombinant Antibody (TAB-179) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
| TAB-457CQ | Anti-Human TNFRSF9 Recombinant Antibody (TAB-457CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G063S | Anti-TNFRSF9 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-064LC | Recombinant Anti-Human TNFRSF9 Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-064LC-1 | Recombinant Anti-Human TNFRSF9 Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0611CLV | Human Anti-TNFRSF9 Recombinant Antibody (TAB-0611CLV) | ELISA, FC | Humanized IgG1 |
| TAB-0612CLV | Human Anti-TNFRSF9 Recombinant Antibody (TAB-0612CLV) | ELISA, FC | Humanized IgG4 |
| TAB-0611CLV-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0611CLV-F(E)) | ELISA, FC | Humanized Fab |
| TAB-0612CLV-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0612CLV-F(E)) | ELISA | Humanized Fab |
| TAB-0611CLV-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0611CLV-S(P)) | ELISA, FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0613CLV | Human Anti-TNFRSF9 Recombinant Antibody (TAB-0613CLV) | ELISA | Chimeric (mouse/human) IgG1 |
| TAB-0614CLV | Human Anti-TNFRSF9 Recombinant Antibody (TAB-0614CLV) | ELISA | Chimeric (mouse/human) IgG1 |
| TAB-0613CLV-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (TAB-0613CLV-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-0613CLV-S(P) | Mouse Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0613CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0614CLV-S(P) | Mouse Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (TAB-0614CLV-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2167CQ | Rat Anti-Tnfrsf9 Recombinant Antibody (clone CBL332) | Block, WB | Rat IgG2b |
| NEUT-2168CQ | Hamster Anti-Tnfrsf9 Recombinant Antibody (clone 17B5) | FC, Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2169CQ | Rat Anti-Tnfrsf9 Recombinant Antibody (NEUT-2169CQ) | Neut, WB | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0053-FY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0053-FY) | ELISA | Human IgG2 |
| HPAB-0809LY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0809LY) | FC, FuncS | Human IgG1 |
| HPAB-0810LY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0810LY) | FC, FuncS | Human IgG1 |
| HPAB-0811LY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0811LY) | FC, FuncS | Human IgG1 |
| HPAB-0812LY | Human Anti-TNFRSF9 Recombinant Antibody (HPAB-0812LY) | FC, FuncS | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0809LY-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0809LY-S(P)) | FC, FuncS | Human scfv |
| HPAB-0810LY-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0810LY-S(P)) | FC, FuncS | Human scfv |
| HPAB-0811LY-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0811LY-S(P)) | FC, FuncS | Human scfv |
| HPAB-0812LY-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0812LY-S(P)) | FC, FuncS | Human scfv |
| HPAB-0813LY-S(P) | Human Anti-TNFRSF9 Recombinant Antibody; scFv Fragment (HPAB-0813LY-S(P)) | FC, FuncS | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0809LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0809LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0810LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0810LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0811LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0811LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0812LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0812LY-F(E)) | FC, FuncS | Human Fab |
| HPAB-0813LY-F(E) | Human Anti-TNFRSF9 Recombinant Antibody; Fab Fragment (HPAB-0813LY-F(E)) | FC, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-457CQ | Afuco™ Anti-TNFRSF9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-457CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY51 | Rat Anti-Tnfrsf9 Agonistic Antibody (VS-0724-XY51) | Agonistic assays | Rat IgG2a |
| VS-0724-XY52 | Rabbit Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY52) | FC, Agonistic assays, CyTOF® | Rabbit IgG |
| VS-0724-XY53 | Human Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY53) | ELISA, Agonistic assays | Human IgG1 |
| VS-0724-XY54 | Rabbit Anti-TNFRSF9 Agonistic Antibody (clone RbBBK4) | ELISA, FC, Agonistic assays | Rabbit IgG, kappa |
| VS-0724-XY55 | Mouse Anti-TNFRSF9 Agonistic Antibody (VS-0724-XY55) | ELISA, FC, Agonistic assays | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY76 | Mouse Anti-NHP TNFRSF9 Recombinant Antibody (VS-1024-XY76) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY224 | CytoStream™ Rat Anti-TNFRSF9 Recombinant Antibody (VS-0225-XY224) | FC | Rat IgG1, kappa |
| VS-0225-XY225 | CytoStream™ Mouse Anti-TNFRSF9 Recombinant Antibody (VS-0225-XY225) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY100 | Human Anti-TNFRSF9 (clone 39E3) scFv-Fc Chimera | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC223 | Recombinant Anti-TNFRSF9 Vesicular Antibody, EV Displayed (VS-0425-YC223) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7386 | Anti-TNFRSF9 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC236 | Recombinant Anti-TNFRSF9 Biparatopic Antibody, Tandem scFv | ELISA, IF, IP | Tandem scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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