Anti-Human C5 Recombinant Antibody (TAB-453CQ) (CAT#: TAB-453CQ)
Recombinant monoclonal antibody to C5. This antibody is a human monoclonal antibody that binds specifically to C5, blocking its cleavage into C5a and C5b.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in SDS-PAGE
SDS-PAGE analysis of TAB-453CQ in non-reduced (right) and reduced (left) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
SEC-HPLC
Figure 2 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in SEC-HPLC
The purity of TAB-453CQ was greater than 95% as determined by HPLC.
ELISA
Figure 3 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in ELISA
Sandwich ELISA analysis of TAB-453CQ was performed by coating with TAB-453CQ and Recombinant Human C5 (his tag).
The secondary antibody: HRP-Anti-His tag
WB
Figure 4 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in WB
Western blot analysis of TAB-453CQ was performed by loading Recombinant Human C5 (His Tag).
TAB-453CQ incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane1: Reducing antigen (0.1 μg)
Lane2: Reducing antigen (0.3 μg)
Lane3: Reducing antigen (0.6 μg)
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1, λ2
- Specificity
- Human C5
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
- Conjugate
- Unconjugated
- Related Disease
- Choroiditis
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
Related Resources
Please refer to Tesidolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tesidolumab.
Systemic Lupus Erythematosus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-028 | Human Anti-C5 Recombinant Antibody scFv Fragment (PSBL-028) | Neut, FuncS | Human scFv |
| HPAB-0655LY-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-0655LY-S(P)) | IP, RIA, ELISA, WB | Mouse scfv |
| HPAB-0656LY-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-0656LY-S(P)) | IP, RIA, ELISA, WB | Mouse scfv |
| HPAB-0657LY-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-0657LY-S(P)) | IP, RIA, ELISA, WB | Mouse scfv |
| HPAB-0080-WJ-S(P) | Human Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-0080-WJ-S(P)) | ELISA, FC | Humanized scFv |
Customer Reviews and Q&As
Customer Review
Q&As
Highly specific medication
We've seen a significant reduction in adverse effects with Tesidolumab compared to older treatments. It's a highly specific medication, which minimizes off-target issues.
Impressive specificity and potency
The specificity and potency of Tesidolumab in targeting C5 are impressive. It represents a major leap forward in our ability to manage complement-mediated diseases effectively.
Manageable side effect
In our trials, Tesidolumab consistently provided therapeutic benefits with a manageable side effect profile. Its role in complement inhibition cannot be overstated.
Ba****a
Excellent for ELISA
Excellent for ELISA
Nice ELISA data of the anti-C5 antibody to human C5 protein, aa 19-1676.
19.Oct,24
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-453CQ, RRID: AB_3111952)
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