Rabbit Anti-APC Recombinant Antibody (clone CBACN-035)
CAT#: MRO-0106-CN
This antibody is a rabbit monoclonal antibody that is capable of binding to APC.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13362/1401_C6_5_selected.jpg
Normal Tissue
Figure 2 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong positivity in neuropil.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13349/165147_B_9_5_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13349/165147_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13349/165147_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13349/165147_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Collecting ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Distal tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13349/165147_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13349/165147_A_6_6.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134982-APC
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Specifications
- Immunogen
- Human APC aa 50-300
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human
- Species Reactivity
- Human, Rat
- Clone
- CBACN-035
- Applications
- WB, IF, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by analysis by SDS-PAGE
- Format
- Liquid
- Buffer
- 1*TBS, pH 7.4, 1% BSA, 40% Glycerol
- Preservative
- 0.05% Sodium Azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- APC, WNT Signaling Pathway Regulator; Protein Phosphatase 1, Regulatory Subunit 46; Deleted In Polyposis 2.5; DP2.5; Adenomatosis Polyposis Coli Tumor Suppressor; Truncated Adenomatosis Polyposis Coli; Adenomatous Polyposis Coli Protein; WNT Signaling Pathway Regulator; Adenomatosis Polyposis Coli;
- Gene ID
- 324
- UniProt ID
- P25054
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Related Diseases
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Related Signaling Pathways
Canonical Wnt Signaling Pathway
JAK-STAT Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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|---|---|---|---|
| MOB-72 | Recombinant Anti-human APC Antibody | ELISA, WB, FC, FuncS | IgG |
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| VS3-XY79 | Mouse Anti-APC Recombinant Antibody (clone 1F7G2) | FC | Mouse IgG1 |
| VS3-FY82 | Recombinant Rabbit Anti-APC Antibody (clone R06-2E4) | WB, ICC, IF, IP | Rabbit IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-72-F(E) | Recombinant Anti-human APC Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| MHH-72-F(E) | Recombinant Human Anti-human APC Antibody Fab Fragment | FC, Neut, Biosensors, FuncS | Fab |
| HPAB-0095-WJ-F(E) | Human Anti-APC Recombinant Antibody; Fab Fragment (HPAB-0095-WJ-F(E)) | ELISA | Humanized Fab |
| HPAB-J0036-YC-F(E) | Mouse Anti-aPC Recombinant Antibody; Fab Fragment (HPAB-J0036-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-J0037-YC-F(E) | Mouse Anti-aPC Recombinant Antibody; Fab Fragment (HPAB-J0037-YC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-72-S(P) | Recombinant Anti-human APC Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| HPAB-J0036-YC-S(P) | Mouse Anti-aPC Recombinant Antibody; scFv Fragment (HPAB-J0036-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-J0037-YC-S(P) | Mouse Anti-aPC Recombinant Antibody; scFv Fragment (HPAB-J0037-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-J0038-YC-S(P) | Mouse Anti-aPC Recombinant Antibody; scFv Fragment (HPAB-J0038-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-J0039-YC-S(P) | Mouse Anti-aPC Recombinant Antibody; scFv Fragment (HPAB-J0039-YC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-241CT-F(E) | Mouse Anti-aPC Recombinant Antibody; Fab Fragment (TAB-241CT-F(E)) | Non-neutralizing | Mouse Fab |
| TAB-242CT-F(E) | Human Anti-aPC Recombinant Antibody; Fab Fragment (TAB-242CT-F(E)) | ELISA, WB | Human Fab |
| TAB-243CT-F(E) | Human Anti-aPC Recombinant Antibody; Fab Fragment (TAB-243CT-F(E)) | ELISA, WB | Human Fab |
| TAB-244CT-F(E) | Human Anti-aPC Recombinant Antibody; Fab Fragment (TAB-244CT-F(E)) | ELISA, WB | Human Fab |
| TAB-245CT-F(E) | Human Anti-aPC Recombinant Antibody; Fab Fragment (TAB-245CT-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0199 | Hi-Affi™ Rabbit Anti-APC Recombinant Antibody (clone DS199AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY127 | Anti-APC Immunohistochemistry Kit | IHC | |
| VS-0525-XY439 | Anti-Mouse APC Immunohistochemistry Kit | IHC | |
| VS-0525-XY438 | Anti-Human APC Immunohistochemistry Kit | IHC |
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