Mouse Anti-CD37 Recombinant Antibody Hexamer (VS-0924-YC112), CDC Enhanced (CAT#: VS-0924-YC112)

The product is a hexameric mouse anti-CD37 antibody with enhanced complement-dependent cytotoxicity (CDC) activity. This IgG1 antibody targeting human CD37 has been engineered with hexamerization-enhancing mutations to promote hexamer formation, facilitating optimal C1q binding and augmenting CDC efficacy.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Mouse
  • Type
  • Antibody hexamer
  • Specificity
  • Human CD37
  • Species Reactivity
  • Human
  • Molecule Class
  • ~ 900 kDa
  • Applications
  • FC, Inhib, CDC
  • Conjugate
  • None
  • Related Disease
  • Type 1 Diabetes, Agents for; Multiple Sclerosis, Agents for; Rheumatoid Arthritis

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein G purified
  • Purity
  • >95% determined as SDS-PAGE and SEC-HPLC
  • Aggregation
  • <5%
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD37 Molecule; Tetraspanin-26; CD37 Antigen; Tspan-26; TSPAN26; Cell Differentiation Antigen 37; Leukocyte Surface Antigen CD37; Leukocyte Antigen CD37; GP52-40
  • Long Name
  • CD37 Molecule
  • Sequence Similarities
  • Belongs to the tetraspanin (TM4SF) family.
  • Cellular Localization
  • Cell membrane; Multi-pass membrane protein
  • Post Translation Modifications
  • Tyrosine phosphorylated; leading to activation of downstream signaling pathways. ( P11049-CD37_HUMAN )
    Glycosylation at Asn170, Asn183, and Asn188 ( NX_P11049 [NX_P11049-1] )

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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