Mouse Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-0163-FY-S(P))

Name: Mouse Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-0163-FY-S(P))
SKU: HPAB-0163-FY-S(P)
Rating: 5 (1 reviews)

CAT#: HPAB-0163-FY-S(P)

This is a recombinant Mouse antibody that specifically targets CD37. It binds to CD37 in order to deplete B-cells, including non-cancerous B-cells. HPAB-0163-FY-S(P) antibody is the scfv fragment antibody form of HPAB-0163-FY antibody. Single-chain variable fragments (scFvs) are artificial constructs consisting of the variable regions of the immunoglobulin heavy and light chains connected by a peptide linker.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEL

Immunofluorescent staining of human cell line HEL shows localization to plasma membrane & the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/1848_F10_26_cr5abb8def07051_selected.jpg

Normal Tissue Figure 2 Tonsil

High expression

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_A_5_8_val_selected.jpg

Normal Tissue Figure 3 Colon

Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_9_3.jpg

Normal Tissue Figure 4 Lymph node

Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_7_8.jpg

Normal Tissue Figure 5 Spleen

Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_B_8_4.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (Daudi, HMC-1, RPMI-8226, THP-1, U-698, U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104894-CD37

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Specifications

Host Species
Mouse

Type
Mouse scFv

Specificity
Human CD37

Species Reactivity
Human

Applications
FC, Inhib

Related Disease
Type 1 Diabetes, Agents for; Multiple Sclerosis, Agents for; Rheumatoid Arthritis

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
CD37 Molecule; Tetraspanin-26; CD37 Antigen; Tspan-26; TSPAN26; Cell Differentiation Antigen 37; Leukocyte Surface Antigen CD37; Leukocyte Antigen CD37; GP52-40

Gene ID
951

UniProt ID
P11049

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0163-FY-S(P).pdf

MSDS

MSDS - HPAB-0163-FY-S(P).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
HPAB-0159-FY-S(P)	Mouse Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-0159-FY-S(P))	Activ, Depletion, FuncS, Inhib	Mouse scFv
HPAB-0164-FY-S(P)	Mouse Anti-CD37 Recombinant Antibody; scFv Fragment (HPAB-0164-FY-S(P))	FC, Inhib	Mouse scFv
HPAB-AP033-YC-S(P)	Human Anti-CD37 Recombinant Antibody (clone A2); scFv Fragment	FuncS	Human scFv
HPAB-AP034-YC-S(P)	Human Anti-CD37 Recombinant Antibody (clone B2); scFv Fragment	FuncS	Human scFv
HPAB-1045-FY-F(E)	Human Anti-CD37 Recombinant Antibody; Fab Fragment (HPAB-1045-FY-F(E))	FC, ELISA	Humanized Fab

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