Anti-Human CD37 Recombinant Antibody (Otlertuzumab) (CAT#: TAB-904)
Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD37. Otlertuzumab is a humanized monoclonal antibody designed for the treatment of cancer
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Figure 1 Serum concentrations of otlertuzumab were measured at multiple time points throughout the dosing cycle and mean concentrations over time are plotted for all 3 NHL treatment groups.
Mean otlertuzumab concentrations versus nominal time. Concentrations were similar between non-Hodgkin lymphoma (NHL) types.
(2015). Otlertuzumab (tru‐016), an anti‐cd37 monospecific adaptir™ therapeutic protein, for relapsed or refractory nhl patients. British Journal of Haematology, 168(1), 38-45.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- VH - V-kappa - CH2 - CH3
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF, ICC
- CAS
- 1372645-37-8
- Generic Name
- Otlertuzumab
- MW
- 107.5 kDa
- Related Disease
- Chronic lymphocytic leukemia (CLL)
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Applications
- Application Notes
- The CD37 antibody has been reported in applications of PK.
Target
- Alternative Names
- Otlertuzumab;1372645-37-8;TRU-016;CAS-024;SMIP-016;CD37;CD37 molecule;CD37 antigen;leukocyte antigen CD37;TSPAN26;tspan-26;tetraspanin-26;leukocyte surface antigen CD37;cell differentiation antigen 37;GP52-40;MGC120234
- Gene ID
- 951
- UniProt ID
- P11049
Related Resources
Please refer to Otlertuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Otlertuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1367z | Mouse Anti-CD37 Recombinant Antibody (clone 41C4) | WB, IP, IF, IHC, ELISA | Mouse IgG2b, κ |
| HPAB-AP033-YC | Human Anti-CD37 Recombinant Antibody (clone A2) | FuncS | Human IgG |
| HPAB-AP034-YC | Human Anti-CD37 Recombinant Antibody (clone B2) | FuncS | Human IgG |
| HPAB-1045-FY | Human Anti-CD37 Recombinant Antibody (HPAB-1045-FY) | FC, ELISA | Humanized IgG |
| VS11-QX31 | Mouse Anti-CD37 Recombinant Antibody [clone IPO-24 (ZC37-24)] | FC, IF, IHC | Mouse IgG2b, κ |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-904, RRID: AB_3112020)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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