Human Anti-CD37 Recombinant Antibody Fab Fragment (TAB-0272CL-F(E))

Name: Human Anti-CD37 Recombinant Antibody Fab Fragment (TAB-0272CL-F(E))
SKU: TAB-0272CL-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-0272CL-F(E)

The chimeric anti-CD37 antibody is derived from a murine monoclonal antibody. The target CD37 is a member of the tetraspanin superfamily, which is a heavily glycosylated cell surface molecule with four transmembrane domains and two extracellular loops. For the function of CD37 in regulating cell development, activation, grow and motility, the anti-CD37 antibody can be useful in immunotherapies and radioimmunotherapies that are base on B-cell depletion, B cell malignancies and autoimmune conditions.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEL

Immunofluorescent staining of human cell line HEL shows localization to plasma membrane & the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/1848_F10_26_cr5abb8def07051_selected.jpg

Normal Tissue Figure 2 Tonsil

High expression

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_A_5_8_val_selected.jpg

Normal Tissue Figure 3 Colon

Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_9_3.jpg

Normal Tissue Figure 4 Lymph node

Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_7_8.jpg

Normal Tissue Figure 5 Spleen

Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_B_8_4.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (Daudi, HMC-1, RPMI-8226, THP-1, U-698, U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104894-CD37

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Specifications

Host Species
Human

Type
Chimeric (mouse/human)

Specificity
Human

Related Disease
Hematologic cancer, B cell malignancies, autoimmune conditions

Target

Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37;

Gene ID
951

UniProt ID
P11049

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-0272CL-F(E).pdf

MSDS

MSDS - TAB-0272CL-F(E).pdf

COA

Certificate of Analysis Lookup

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CAT	Product Name	Application	Type
TAB-0272CL	Human Anti-CD37 Recombinant Antibody (TAB-0272CL)	ELISA, WB	Chimeric (mouse/human)
TAB-0273CL	Human Anti-CD37 Recombinant Antibody (TAB-0273CL)	Block	Chimeric (mouse/human)
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TAB-0273CL-S(P)	Human Anti-CD37 Recombinant Antibody scFv Fragment (TAB-0273CL-S(P))	Block	Chimeric (mouse/human)
TAB-0273CL-F(E)	Human Anti-CD37 Recombinant Antibody Fab Fragment (TAB-0273CL-F(E))	Block	Chimeric (mouse/human)

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CAT	Product Name	Application	Type
HPAB-0159-FY-F(E)	Mouse Anti-CD37 Recombinant Antibody; Fab Fragment (HPAB-0159-FY-F(E))	Activ, Depletion, FuncS, Inhib	Mouse Fab
HPAB-0163-FY-F(E)	Mouse Anti-CD37 Recombinant Antibody; Fab Fragment (HPAB-0163-FY-F(E))	FC, Inhib	Mouse Fab
HPAB-0164-FY-F(E)	Mouse Anti-CD37 Recombinant Antibody; Fab Fragment (HPAB-0164-FY-F(E))	FC, Inhib	Mouse Fab
HPAB-AP033-YC-F(E)	Human Anti-CD37 Recombinant Antibody (clone A2); Fab Fragment	FuncS	Human Fab
HPAB-AP034-YC-F(E)	Human Anti-CD37 Recombinant Antibody (clone B2); Fab Fragment	FuncS	Human Fab

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