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    Mouse Anti-CD74 Recombinant Antibody (clone LN-2) (CAT#: VS11-QX44)

    This product is a recombinant mouse antibody that recognizes CD74. The LN-2 antibody is specific for CD74, binding to an epitope located within 60 amino acids of the extracytoplasmic, C-terminus of the protein. This antibody can be used for the following applications: WB, IHC, IF, FC, ELISA, IP.

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    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/if_selected.jpg
    Figure 2 IHC staining of human spleen
    Figure 2 IHC staining of human spleen
    (Immunohistochemical staining of human spleen shows strong granular cytoplasmic positivity.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10592/ihc_selected.jpg
    Figure 3 IHC staining of human tonsil
    Figure 3 IHC staining of human tonsil
    (Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in germinal center cells and non-germinal center cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79994/170659_A_6_8_selected.jpg
    Figure 4 IF staining of human cell line U-251 MG
    Figure 4 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/203_F11_1_blue_red_green.jpg
    Normal Tissue
    Figure 5 Colon
    Figure 5 Colon
    (Mucosal lymphoid cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_7_3.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_5.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_8_8.jpg
    Figure 8 Tonsil
    Figure 8 Tonsil
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2506/6593_A_6_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)
    Figure 9 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, HDLM-2, REH, RPMI-8226, U-266/70, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000019582-CD74

    Specifications

    • Immunogen
    • SU-DHL-4 lymphoma cells
    • Host Species
    • Mouse
    • Derivation
    • Mouse
    • Type
    • Mouse IgG1, κ
    • Specificity
    • This antibody is specific for CD74.
    • Species Reactivity
    • Human, Mouse, Rat
    • Clone
    • LN-2
    • Applications
    • WB, IHC, IF, FC, ELISA, IP
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • 1 mg/mL (Please refer to the vial label for the specific concentration.)
    • Buffer
    • 0.2 μm filtered solution in PBS
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipped at 4°C.

    Target

    • Alternative Names
    • II; p33; DHLAG; HLADG; Ia-GAMMA
    • Long Name
    • HLA class II histocompatibility antigen gamma chain
    • Cellular Localization
    • Golgi apparatus

    Recommended Products

    Isotype Control

    Recommended Dilution Buffer

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    NAB-466-VHH Recombinant Anti-Human CD74 VHH Single Domain Antibody FUNC, FA, IP, ChiP Llama VHH
    TAB-0004CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0004CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
    TAB-0005CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0005CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
    TAB-0006CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0006CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH
    TAB-0007CL-VHH Anti-Human CD74 VHH Single Domain Antibody (TAB-0007CL-VHH) ELISA, FC, Internalization, Inhib, FuncS VHH

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