Human Anti-FGFR2 Antibody (M048-D01), CHO Stable Cell Pool

Name: Human Anti-FGFR2 Antibody (M048-D01), CHO Stable Cell Pool
SKU: VS-1025-QX103
Rating: 5 (1 reviews)

CAT#: VS-1025-QX103

This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant M048-D01. M048-D01 is a Human monoclonal antibody that targets FGFR2. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of M048-D01 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEK 293

Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm, cell junctions & vesicles.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/if_selected.jpg

Normal Tissue Figure 2 IHC staining of human stomach

Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/ihc_selected.jpg

Normal Tissue Figure 3 IHC staining of human skin

Immunohistochemical staining of human skin shows strong ctyoplasmic positivity in keratinocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_1_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_5.jpg

Normal Tissue Figure 5 Colon

Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_7_3.jpg

Normal Tissue Figure 6 Testis

Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_4_6.jpg

Normal Tissue Figure 7 Lymph node

Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_9_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (AN3-CA, BEWO, CACO-2, HaCaT, HAP1, NTERA-2, T-47d)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000066468-FGFR2

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Specifications

Host Cell
CHO

Product Type
Stable Cell Pool

Cell Viability
>90%

Mycoplasma Detection
Negative

Bacteria Detection
Negative

Growth Properties
Suspension

Culture Medium
VersaCHO™ Medium (VS-1025-QX582)

Complete Growth Medium
VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)

Freeze Medium
90% VersaCHO™ Medium, 10% DMSO

Growth Conditions
37°C, 5% CO₂

Size
Each vial contains at least 1×10^6 cells in 1 mL

Shipping
Dry ice

Storage
Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.

Antibody Overview

Host Species
Human

Antibody Type
Human IgG1, λ

Clone
M048-D01

Target
FGFR2

Species Reactivity
Human, Mouse

Target

Alternative Names
Fibroblast Growth Factor Receptor 2; Keratinocyte Growth Factor Receptor; Bacteria-Expressed Kinase; EC 2.7.10.1; K-SAM; KGFR; BEK; Protein Tyrosine Kinase, Receptor Like 14; BEK Fibroblast Growth Factor Receptor; Craniofacial Dysostosis 1; Jackson-Weiss Syndrome; Pfeiffer Syndrome; Crouzon Syndrome; CD332 Antigen; EC 2.7.10; FGFR-2; BFR-1; CD332; BBDS; CEK3; ECT1; TK14; TK25; CFD1; KSAM; JWS

Gene ID
2263

UniProt ID
P21802

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Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance

Downloadable Resources

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Datasheet

Datasheet - VS-1025-QX103.pdf

MSDS

MSDS - VS-1025-QX103.pdf

COA

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