Human Anti-FN1 Recombinant Antibody (clone ME4C) (CAT#: FAMAB-0105YC)
Provided is a specific monoclonal antibody against the ED-B domain of Fibronectin, a maker of angiogenesis. ME4C binds to the ED-B domain with a dissociation constant in the nanomolar range and specifically stains tumors blood vessels of human and murine origin.
Specific Inquiry
IHC
Figure 1 Immunohistochemical experiments with the antibody ME4C.
(A) A section of glioblastoma multiforme specimen. The typical glomerulus-like vascular structures are stained in red by the scFv (ME4C). Scale bar, 100 µm. (B) A section of SKMEL-28 human melanoma, grafted in a nude mouse, stained with scFv (ME4C). The antibody localises around vascular structures and proliferating cells. Scale bar, 50 µm.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human FN1
- Species Reactivity
- Human, Mouse
- Clone
- ME4C
- Applications
- ELISA, IHC
- Related Disease
- Tumor
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF
Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1294z | Mouse Anti-FN1 Recombinant Antibody (clone 6H4) | IHC, IP, WB | Mouse IgG2b, κ |
| MRO-0589-CN | Rabbit Anti-FN1 Recombinant Antibody (clone JF0582) | WB, IF, IHC | Rabbit IgG |
| HPAB-1110-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1110-FY) | IHC | Human IgG |
| HPAB-1111-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1111-FY) | IHC | Human IgG |
| HPAB-1112-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1112-FY) | IHC | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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