Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced (CAT#: AFC-TAB-218)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL13. Tralokinumab is a human monoclonal antibody which targets the cytokine interleukin 13, and is designed for the treatment of asthma and inflammatory diseases.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Tralokinumab
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Generic Name
- Tralokinumab
- Related Disease
- Asthma, severe
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tralokinumab; 1044515-88-9; CAT-354; BAK502G9; IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13;
- Gene ID
- 3596
- UniProt ID
- P35225
Related Resources
Please refer to Tralokinumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tralokinumab.
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Tralokinumab"
Anti-Human IL13 Recombinant Antibody (Tralokinumab)Recombinant monoclonal antibody to IL13. Tralokinumab is a human monoclonal antibody which targets the cytokine interleukin 13, and is designed for the treatment of asthma and inflammatory diseases.
See other products for "IL13"
Select a product category from the dropdown menu below to view related products.
Please select product type
Recombinant Antibody
Human Antibody
Mouse Antibody
Chimeric Antibody
Humanized Antibody
Neutralizing Antibody
Rabbit Monoclonal Antibody
ADCC Enhanced Antibody
scFv Fragment Antibody
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1287z | Mouse Anti-IL13 Recombinant Antibody (clone 39B4) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| HPAB-0355-WJ | Human Anti-IL13 Recombinant Antibody (clone 13C5.5) | ELISA, Neut, FuncS | Humanized IgG1, κ |
| VS3-WK1714 | Recombinant Rabbit Anti-IL13 Capture Antibody (clone R09-6G8) | ELISA | Rabbit IgG |
| VS3-WK1715 | Recombinant Rabbit Anti-IL13 Detection Antibody (clone R05-9S9) | ELISA | Rabbit IgG |
| VS3-WK1764 | Recombinant Rabbit Anti-IL13 Capture Antibody (clone R04-5T4) | ELISA | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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