Human Anti-IL13 Recombinant Antibody (clone V2.11) (CAT#: HPAB-1742-FY)
This product is a recombinant antibody that recognizes IL13. The monoclonal antibody V2.11 reacts with the epitope of IL13. The inhibitory activity of V2.11 was comparable to that of sIL-13Ra2-Fc.
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Neut
Figure 1 A graph depicts the neutralization of NHP IL-13 activity by humanized MJ2-7 v.211.
Neut
Figure 2 A graph depicts the neutralization of NHP IL-13 activity by humanized MJ2-7 v.211.
SPR
Figure 3 A graph depicts the binding of varying concentrations (0.09-600 nM) of NHP IL-13 to captured hMJ2-7 v.2-11 antibody.
Inhib
Figure 4 Show total of BAL cells/ml in BAL fluids in control and antibody-treated cynomolgus monkeys pre- and post-Ascaris challenge.
Inhib
Figure 5 Depicts a decrease in eotaxin levels in concentrated BAL fluids from cynomolgus monkeys treated with mAb 13.2-(gray circles) or MJ2-7-(gray triangles) antibodies compared to a control (dark circles).
RIA
![Figure 6 Shows the concentrations of [125I]-labeled humanized 13.2v.2 anti-IL-13 antibody and [251I]-labeled humanized MJ2-7v.2-11 antibody in various mouse and rat tissue, respectively.](https://img.creativebiolabs.net/productimages/HPAB-1742-FY-6.png)
Figure 6 Shows the concentrations of [125I]-labeled humanized 13.2v.2 anti-IL-13 antibody and [251I]-labeled humanized MJ2-7v.2-11 antibody in various mouse and rat tissue, respectively.
ELISA
Figure 7 Showing observed and predicted IL-13 and anti-IL-13 antibody levels over time.
1 mg/kg of humanized MJ2-7v.2-11 antibody was administered to naïve cynomolgus monkeys. Total IL-13 and humanized MJ2-7v.2-11 serum levels were quantified over a period of 0-45 days using a specific ELISA.
ELISA
Figure 8 Showing observed and predicted IL-13 and anti-IL-13 antibody levels over time.
1 mg/kg of humanized MJ2-7v.2-11 antibody was administered to naïve cynomolgus monkeys. Total IL-13 and humanized MJ2-7v.2-11 serum levels were quantified over a period of 0-45 days using a specific ELISA.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human IL13
- Species Reactivity
- Human
- Clone
- V2.11
- Applications
- Neut, SPR, Inhib, RIA, ELISA
- Related Disease
- Disorders, Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IL13 antibody has been reported in applications of Neutralization, Surface Plasmon Resonance, Inhibition, Radioimmunoassay, Enzyme-linked Immunosorbent Assay.
ELISA: 1 mg/kg.
Target
Related Resources
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218 | Anti-Human IL13 Recombinant Antibody (Tralokinumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - lambda |
| TAB-068ZJ | Anti-Human IL-13 Recombinant Antibody (01471/G6) | WB, ELISA, Neut | Human antibody |
| TAB-069ZJ | Human Anti-IL13 Recombinant Antibody (TAB-069ZJ) | ELISA, Neut, FC | Human IgG |
| PABX-115-S (P) | Recombinant Human Anti-IL-13 Antibody scFv Fragment (C836) | WB, ELISA, FuncS | scFv |
| TAB-017ML | Anti-Human IL13 Recombinant Antibody (TAB-017ML) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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