Human Anti-IL1B Recombinant Antibody (clone 048Ab-4) (CAT#: HPAB-N0148-YC)
The anti-IL-1beta monoclonal antibody can prevent bonding of human IL-1beta and human IL-1R. By means of bonding of IL-1beta, blocking of IL-1beta and a receptor signal channel of the IL-1beta, unnecessary IL-1beta initial induced heat transfer, amplified lymphocyte responses and stimulation acute stage responses can be reduced. The anti-IL-1beta monoclonal antibody can be used for detecting IL-1beta expressions and used for prevention and treatment of cryopyrin-associated periodic syndromes.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (BJ hTERT+, HBEC3-KT, HMC-1, hTEC/SVTERT24-B, hTERT-RPE1, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Figure 1 RNA cell line category: Cell line enhanced (BJ hTERT+, HBEC3-KT, HMC-1, hTEC/SVTERT24-B, hTERT-RPE1, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG
- Specificity
- Human IL1B
- Species Reactivity
- Human
- Clone
- 048Ab-4
- Applications
- ELISA
- Related Disease
- Cryopyrin-Associated Periodic Syndromes
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Rheumatoid Arthritis
Maturity Onset Diabetes of the Young
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-232CT | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (ch47F11) | Inhibition | Chimeric antibody (mouse/human) |
| TAB-237CT | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (chSK48-E26) | ELISA, Neut | Chimeric antibody (mouse/human) |
| TAB-237CT-F(E) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody Fab Fragment (chSK48-E26) | ELISA, Neut | Chimeric antibody (mouse/human) |
| TAB-543LC | Anti-human IL1B Recombinant Antibody, Chimeric (TAB-543LC) | ELISA | Chimeric antibody (mouse/human) |
| TAB-543LC-F(E) | Anti-human IL1B Fab Fragment, Chimeric | ELISA | Chimeric antibody (mouse/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-230CT-S(P) | Mouse Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-230CT-S(P)) | ELISA | Mouse scFv |
| TAB-231CT-S(P) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody scFv Fragment (47F11) | Inhibition | |
| TAB-234CT-S(P) | Rabbit Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-234CT-S(P)) | FC, ELISA, Neut | Rabbit scFv |
| TAB-235CT-S(P) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody scFv Fragment (SK48-E26) | ELISA, Neut | |
| TAB-548LC-S(P) | Rabbit Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-548LC-S(P)) | ELISA, SPR | Rabbit scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-233CT-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-233CT-S(P)) | ELISA | Humanized scFv |
| TAB-236CT-S(P) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody scFv Fragment (huSK48-E26) | ELISA, Neut | Humanized antibody |
| TAB-233CT-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (TAB-233CT-F(E)) | ELISA | Humanized Fab |
| TAB-544LC-S(P) | Anti-human IL1B scFv Fragment, Humanized | ELISA | Humanized antibody |
| TAB-549LC-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-549LC-S(P)) | ELISA, SPR | Humanized scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-545LC | Human Anti-IL1B Recombinant Antibody (TAB-545LC) | ELISA, Inhib, Neut | Human IgG1 |
| TAB-546LC | Human Anti-IL1B Recombinant Antibody (TAB-546LC) | ELISA, FC, Neut | Human IgG1 |
| TAB-550LC | Anti-human IL1B Recombinant Antibody (9.5.2) (TAB-550LC) | ELISA, Inhib, FuncS | Human antibody |
| TAB-551LC | Anti-human IL1B Recombinant Antibody (5.5.1) (TAB-551LC) | ELISA, Inhib | Human antibody |
| TAB-552LC | Anti-human IL1B Recombinant Antibody (8.18.1) (TAB-552LC) | ELISA, Inhib | Human antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0282MZ | Chicken Anti-Interleukin-1β Polyclonal IgY | WB, Indirect ELISA | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1271CQ | Recombinant Mouse Anti-IL1B Antibody (CBL665) | Neut | IgG1 |
| NEUT-1272CQ | Mouse Anti-IL1B Recombinant Antibody (clone 4M27) | IHC, Neut, WB | Mouse IgG2 |
| NEUT-1273CQ | Mouse Anti-IL1B Recombinant Antibody (clone 8516.311) | ELISA, WB, Neut | Mouse IgG1 |
| NEUT-1275CQ | Mouse Anti-IL1B Recombinant Antibody (clone 2805R) | ELISA, Neut, WB, ICC | Mouse IgG1 |
| NEUT-1276CQ | Mouse Anti-IL1B Recombinant Antibody (clone CBL697) | Neut, ELISA | Mouse IgG |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1274CQ | Mouse Anti-IL1B Recombinant Antibody (clone B-A15) | Block, FC | Mouse IgG1 |
| NEUT-1285CQ | Mouse Anti-IL1B Recombinant Antibody (clone H1b-27) | ELISA, ELISPOT, Block | Mouse IgG2b, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1798 | Rabbit Anti-IL1B Recombinant Antibody (clone DS1798AB) | WB | Rabbit IgG |
| MOR-4237 | Rabbit Anti-IL1B Recombinant Antibody (clone SI316DS) | ELISA | Rabbit IgG |
| MOR-4238 | Rabbit Anti-IL1B Recombinant Antibody (clone SI317DS) | ELISA | Rabbit IgG |
| MOR-4239 | Rabbit Anti-IL1B Recombinant Antibody (clone SI318DS) | ELISA | Rabbit IgG |
| MOR-4605 | Rabbit Anti-IL1B Recombinant Antibody (clone TH118DS) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0030-YC | Human Anti-IL1B Recombinant Antibody (clone B1) | Inhib, WB, ELISA | Humanized IgG1, κ |
| HPAB-0031-YC | Human Anti-IL1B Recombinant Antibody (clone ABT2-76) | ELISA, Neut | Human IgG |
| HPAB-0032-YC | Human Anti-IL1B Recombinant Antibody (clone AAL160) | Neut, Block | Human IgG1, κ |
| HPAB-0729-FY | Mouse Anti-IL1B Recombinant Antibody (HPAB-0729-FY) | ELISA, Neut | Mouse IgG |
| HPAB-0730-FY | Mouse Anti-IL1B Recombinant Antibody (HPAB-0730-FY) | ELISA, Neut | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0241CQ-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (HPAB-0241CQ-F(E)) | ELISA, FC, Neut | Humanized Fab |
| HPAB-0242CQ-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (HPAB-0242CQ-F(E)) | ELISA, FC, Neut | Humanized Fab |
| HPAB-0243CQ-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (HPAB-0243CQ-F(E)) | ELISA, FC, Neut | Humanized Fab |
| HPAB-0244CQ-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (HPAB-0244CQ-F(E)) | ELISA, FC, Neut | Humanized Fab |
| HPAB-0245CQ-F(E) | Human Anti-IL1B Recombinant Antibody (clone gH3gL3); Fab Fragment | ELISA, Neut | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-021 | Afuco™ Anti-IL1B ADCC Recombinant Antibody (Canakinumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-161 | Afuco™ Anti-IL1B ADCC Recombinant Antibody (Gevokizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0918-WJ-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0918-WJ-S(P)) | ELISA | Humanized scFv |
| HPAB-0919-WJ-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0919-WJ-S(P)) | ELISA | Humanized scFv |
| HPAB-1266WJ-S(P) | Mouse Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-1266WJ-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-1861-FY-F(E) | Human Anti-IL1B Recombinant Antibody (clone Hu007); scFv Fragment | Neut | Humanized scFv |
| PSBS-0021 | Human Anti-IL1B Recombinant Antibody (Clone 4AB007); scFv Fragment | ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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