Rabbit Anti-IL1RAP Recombinant Antibody (clone R05-3B8) (CAT#: VS3-FY2014)
The anti-IL-1 receptor accessory protein antibody detected positive in western blot analysis of IL-1RAcP in HL-60, U251, U87-MG lysates. The recombinant monoclonal antibody exhibits high specificity and affinity for human IL1RAP. It is suitable for use in a variety of assays, including WB, IP.
Specific Inquiry
WB
Figure 1 Anti-IL1RAP Antibody (VS3-FY2014) in WB.
The IL-1RAcP expression in HL-60, U251, U87-MG lysates were detected using the anti-IL-1 Receptor Accessory Protein by western blot assay.
Specifications
- Immunogen
- Recombinant human IL-1RAcP protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL1RAP
- Species Reactivity
- Human
- Clone
- R05-3B8
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 65 kDa, while the observed molecular weight stands at 78 kDa.
- Related Disease
- Autoinflammatory diseases
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Interleukin 1 Receptor Accessory Protein
- Gene ID
- 3556
- UniProt ID
- Q9NPH3
- Sequence Similarities
- Belongs to the interleukin-1 receptor family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn57, Asn107, Asn111, Asn118, Asn196, Asn209, and Asn299 (NX_Q9NPH3 [NX_Q9NPH3-1])
Modification sites at PhosphoSitePlus (Q9NPH3)
Glycosylation from GlyConnect IL1AP_HUMAN (1425)
Glycosylation from GlyGen (Q9NPH3) 9 sites, 13 N-linked glycans (3 sites)
- Protein Refseq
- XP_016861837.1; XP_047304037.1; XP_047304038.1; XP_047304039.1; XP_047304040.1
- Function
- The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).
May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (Probable).
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL1RAP"
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-559 | Recombinant Anti-human IL1RAP Antibody | ELISA, WB, FuncS | IgG |
| HPAB-M0109-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0109-YC) | ELISA | Humanized IgG |
| HPAB-M0110-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0110-YC) | ELISA | Humanized IgG |
| HPAB-M0111-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0111-YC) | ELISA | Humanized IgG |
| HPAB-M0112-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0112-YC) | ELISA | Humanized IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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