AbPlus™ Anti-IL3RA Magnetic Beads (VS-0724-YC1513)

CAT#: VS-0724-YC1513

The AbPlus Anti-IL3RA Magnetic Beads (VS-0724-YC1513) is an innovative affinity resin which is bound with anti-IL3RA specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IL3RA protein under native and denaturing conditions.

Gene Expression
Figure 1 IHC staining of human small intestine Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Kidney Figure 5 Testis Figure 6 Lymph node Figure 7 RNA cell line category: Cell line enhanced (HDLM-2, NB-4, RPMI-8226)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-IL3RA specific antibody
  • Target
  • IL3RA
  • Immunogen
  • Recombinant human IL3RA/CD123, aa 1-305.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
  • Alternative Names
  • Interleukin 3 Receptor Subunit Alpha
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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