Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (HPAB-653-FY-F(E))

Name: Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (HPAB-653-FY-F(E))
SKU: HPAB-653-FY-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-653-FY-F(E)

This product is a recombinant mouse antibody Fab fragment that recognizes SNCA, the pathological accumulation of which causes the development of many neurodegenerative disorders. The Fab antibody binds to an epitope within the recombinant amino acid 113-140 of human SNCA protein. The affinity and specificity of this antibody had been validated by western blot, immunoprecipitation, immunohistochemistry, and enzyme-linked immunosorbent assay. Purified by affinity chromatography, this Fab antibody product could be used in the detection and immunoassay research of neurodegenerative disorders, such as Parkinson's disease and dementia with lewy bodies.

Gene Expression

Normal Tissue Figure 1 High expression in cerebral cortex

Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164874_B_9_5.jpg

Normal Tissue Figure 2 Colon

Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10877/164900_A_7_3.jpg

Normal Tissue Figure 3 Kidney

Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164893_A_7_5.jpg

Normal Tissue Figure 4 Testis

Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164893_A_6_6.jpg

Normal Tissue Figure 5 Bone marrow

Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164874_B_4_4.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (HEL, HUVEC TERT2, RT4, SK-MEL-30, TIME)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000145335-SNCA

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Specifications

Host Species
Mouse

Type
Mouse Fab

Specificity
Human SNCA

Species Reactivity
Human

Applications
WB, IP, ELISA

Related Disease
Parkinson's disease

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Synuclein Alpha; Synuclein, Alpha (Non A4 Component Of Amyloid Precursor); Alpha-Synuclein; PARK1; NACP; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Non A4 Component Of Amyloid Precursor; Non-A4 Component Of Amyloid Precursor;

Gene ID
6622

UniProt ID
P37840

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-653-FY-F(E).pdf

MSDS

MSDS - HPAB-653-FY-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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HPAB-0023-FY-S(P)	Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-0023-FY-S(P))	ELISA	Mouse scFv
HPAB-653-FY-S(P)	Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-653-FY-S(P))	WB, IP, ELISA	Mouse scFv
HPAB-0753-WJ-S(P)	Human Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-0753-WJ-S(P))	ELISA	Human scFv

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