Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (clone 4E6) (CAT#: FAMAB-0324-CN-VHH)
This is a sdAb specifically against human DR5. The DR5 sdAb has great anti-tumor efficacy than conventional agonist antibodies, including durable tumor regressions in a panel of primary patient derived tumor xenografts from colon and pancreatic cancer patients.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51170_B_7_5.jpg

(Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_3.jpg

(Cholangiocytes
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Hepatocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_4.jpg

(Cells in glomeruli
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_8_5.jpg

(Cells in seminiferous ducts
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_6_6.jpg

(Non-germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_8.jpg

(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000120889-TNFRSF10B

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120889-TNFRSF10B
Specifications
- Immunogen
- Soluble recombinant DR5 protein
- Host Species
- Camelid
- Derivation
- Phage display library
- Type
- Camelid VHH
- Specificity
- Human TNFRSF10B
- Species Reactivity
- Human
- Clone
- 4E6
- Applications
- WB, ELISA, FC, IHC, IP
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
- Gene ID
- 8795
- UniProt ID
- O14763
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TNFRSF10B"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1172z | Mouse Anti-TNFRSF10B Recombinant Antibody (clone 40C9) | FC, ICC, IHC, IP, FuncS | Mouse IgG1 |
PABW-057 | Human Anti-TNFRSF10B Recombinant Antibody (clone YSd1) | ELISA | Human IgG |
FN-054CQ | Mouse Anti-TNFRSF10B Recombinant Antibody (clone HS201) | FC, Inhib, ICC, IP | Mouse IgG1 |
HPAB-0672YY | Human Anti-TNFRSF10B Recombinant Antibody (HPAB-0672YY) | ELISA, FuncS | Humanized IgG1 |
HPAB-0673YY | Human Anti-TNFRSF10B Recombinant Antibody (HPAB-0673YY) | ELISA, FuncS | Humanized IgG1 |
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For Research Use Only. Not For Clinical Use.
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