Human Anti-TNFSF11 Recombinant Antibody (clone 2D8) (CAT#: HPAB-1927-FY)
This product is a recombinant antibody that recognizes TNFSF11. The monoclonal antibody 2D8 reacts with the epitope of TNFSF11.
Specific Inquiry
Inhib
Figure 1 A graph shows optical density versus anti-OPGL antibody concentration demonstrating OPGL antibody mediated inhibition of osteoclast formation.
ELISA
Figure 2 Depicts graphs representing the percentage change in serum NTx from baseline following subcutaneous administration at 1.0 mg/kg of anti-OPGL antibodies in Cynomolgus monkeys.
ELISA
Figure 3 Depicts the results of an enzyme immunoassay showing six anti-OPGL antibodies of the invention binding murine OPGL (143-317).
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human TNFSF11
- Species Reactivity
- Human
- Clone
- 2D8
- Applications
- Inhib, ELISA
- Related Disease
- Osteoporosis, bone loss from arthritis, Paget's disease, and osteopenia
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The TNFSF11 antibody has been reported in applications of Inhibition, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- TNF Superfamily Member 11; Tumor Necrosis Factor (Ligand) Superfamily, Member 11; TNF-Related Activation-Induced Cytokine; Osteoclast Differentiation Factor; Osteoprotegerin Ligand; TRANCE; RANKL; OPGL; ODF; Receptor Activator Of Nuclear Factor Kappa B Ligand; Receptor Activator Of Nuclear Factor Kappa-B Ligand
- Gene ID
- 8600
- UniProt ID
- O14788
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-299CT | Anti-Human RANKL Recombinant Antibody (RL1) | ELISA | Human antibody |
| TAB-300CT | Anti-Human RANKL Recombinant Antibody (RL2) | ELISA | Human antibody |
| TAB-301CT | Anti-Human RANKL Recombinant Antibody (RL3) | ELISA | Human antibody |
| TAB-302CT | Anti-Human RANKL Recombinant Antibody (RL4) | ELISA | Human antibody |
| TAB-303CT | Anti-Human RANKL Recombinant Antibody (RL5) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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