Human Anti-TNFSF11 Recombinant Antibody (clone 2D8) (CAT#: HPAB-1927-FY)
This product is a recombinant antibody that recognizes TNFSF11. The monoclonal antibody 2D8 reacts with the epitope of TNFSF11.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 A graph shows optical density versus anti-OPGL antibody concentration demonstrating OPGL antibody mediated inhibition of osteoclast formation.
ELISA
Figure 2 Depicts graphs representing the percentage change in serum NTx from baseline following subcutaneous administration at 1.0 mg/kg of anti-OPGL antibodies in Cynomolgus monkeys.
ELISA
Figure 3 Depicts the results of an enzyme immunoassay showing six anti-OPGL antibodies of the invention binding murine OPGL (143-317).
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human TNFSF11
- Species Reactivity
- Human
- Clone
- 2D8
- Applications
- Inhib, ELISA
- Related Disease
- Osteoporosis, bone loss from arthritis, Paget's disease, and osteopenia
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The TNFSF11 antibody has been reported in applications of Inhibition, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- TNF Superfamily Member 11; Tumor Necrosis Factor (Ligand) Superfamily, Member 11; TNF-Related Activation-Induced Cytokine; Osteoclast Differentiation Factor; Osteoprotegerin Ligand; TRANCE; RANKL; OPGL; ODF; Receptor Activator Of Nuclear Factor Kappa B Ligand; Receptor Activator Of Nuclear Factor Kappa-B Ligand
- Gene ID
- 8600
- UniProt ID
- O14788
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H18 | Human Anti-TNFSF11 Recombinant Antibody (TAB-H18) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Human IgG2 |
| TAB-299CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL1) | ELISA | Human antibody |
| TAB-300CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL2) | ELISA | Human antibody |
| TAB-301CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL3) | ELISA | Human antibody |
| TAB-302CT-S(P) | Anti-Human RANKL Recombinant Antibody scFv Fragment (RL4) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
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