APC-B*27:05/Human BRAF (GRFGLATEK) MHC Tetramer (CAT#: MHC-CN0458)


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • B*27:05
  • Class
  • Class I
  • Antigen
  • BRAF
  • Antigen Species
  • Human
  • Peptide
  • GRFGLATEK
  • Conjugate
  • APC
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
  • Alternative Names
  • NS7; B-raf; BRAF1; RAFB1; B-RAF1

Related Resources

  • Related Signaling Pathways
  • Related Diseases

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "BRAF"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-122-F(E) Recombinant Anti-human BRAF Antibody Fab Fragment IF, Neut, FuncS Fab
MHH-122-F(E) Recombinant Human Anti-human BRAF Antibody Fab Fragment ELISA, WB, Neut, FuncS Fab

scFv Fragment Antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0379 Hi-Affi™ Rabbit Anti-BRAF Recombinant Antibody (clone DS379AB) WB, IHC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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