Mouse Anti-IL2 scFv-Fc Chimera (VS-0325-FY107) (CAT#: VS-0325-FY107)
The anti-IL2 scFv-Fc antibody specifically targets IL-2, a cytokine crucial for T cell proliferation and immune regulation. Its scFv-Fc format enhances its stability and ability to modulate IL-2-mediated immune responses. This antibody is valuable for studying IL-2 signaling pathways and its role in immune system homeostasis.
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Normal Tissue
RNA Expression
Figure 1 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10310/26644_A_7_3.jpg
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10310/26644_A_7_3.jpg
Figure 2 Kidney
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10310/26644_A_8_5.jpg
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10310/26644_A_8_5.jpg
Figure 3 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10310/26644_A_6_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10310/26644_A_6_6.jpg
Figure 4 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000109471-IL2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000109471-IL2
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Mouse IL2
- Species Reactivity
- Mouse
- Applications
- Flow Cytometry, Immunohistochemistry, ELISA, Blocking
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 2
- Gene ID
- 3558
- UniProt ID
- P60568
- Long Name
- Interleukin 2
- Sequence Similarities
- Belongs to the IL-2 family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Thr23
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect IL2_HUMAN (225, 297, 298, 299, 300)
Glycosylation from GlyGen 2 sites, 11 N-linked glycans (1 site), 9 O-linked glycans (2 sites)
- Protein Refseq
- NP_000577.2
- Function
- Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well (PubMed:6608729).
Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production (PubMed:6438535).
Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-093 | Recombinant Anti-Mouse Il2 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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