Recombinant Mouse Anti-CTLA4 Capture Antibody (clone 1A8)
CAT#: VS3-WK1626
This antibody is a mouse recombinant antibody against human CTLA4. The sandwich ELISA was established using matched antibody pair 1A8 and 9C7. The clone 1A8 can be used in ELISA analysis as a capture antibody at a dilution of 1/1000. It was developed by immunization of mouse with recombinant human CTLA4 protein and then was produced as a recombinant antibody. The isotype of this product is mouse IgG1.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
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Specifications
- Immunogen
- Recombinant human CTLA4 protein
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human CTLA4
- Species Reactivity
- Human
- Clone
- 1A8
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.09% sodium azide
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- ELISA: 1/1000
Target
- Alternative Names
- Cytotoxic T-Lymphocyte Associated Protein 4; Insulin-Dependent Diabetes Mellitus 12; Celiac Disease 3; CTLA-4; CD152; Ligand And Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4; Cytotoxic T Lymphocyte Associated Antigen 4 Short Spliced Form; Cytotoxic T-Lymphocyte-Associated Serine Esterase-4; Cytotoxic T-Lymphocyte-Associated Antigen 4; Cytotoxic T-Lymphocyte Protein 4
- Gene ID
- 1493
- UniProt ID
- P16410
- Long Name
- Cytotoxic T-Lymphocyte Associated Protein 4
- Cellular Localization
- Cell membrane, Membrane
- Protein Refseq
- NP_001032720.1
- Function
- Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
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Related Diseases
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Detection antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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| HPAB-0751LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0751LY-F(E)) | FuncS, ELISA | Human Fab |
| HPAB-0752LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0752LY-F(E)) | FuncS, ELISA | Human Fab |
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