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SOX2
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- Mouse Anti-SOX2 Recombinant Antibody (clone 10F10) (VS3-XY1456)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, ICC
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- Mouse Anti-SOX2 Recombinant Antibody (clone 10F10C9) (VS3-QX1044)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Rabbit Anti-SOX2 Polyclonal Antibody (MRO-2197-CN) (MRO-2197-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, ELISA, IHC
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- Mouse Anti-SOX2 Recombinant Antibody (VS3-FY2879) (VS3-FY2879)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB, IHC, ICC, FC
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- Recombinant Mouse Anti-SOX2 Antibody (VS4-CJ123) (VS4-CJ123)
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- Species Reactivity: Human, Porcine, Mouse, Rat
- Type: Mouse IgG2b
- Application: ELISA, WB
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- AbPlus™ Anti-SOX2 Magnetic Beads (VS-0724-YC574) (VS-0724-YC574)
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- Target: SOX2
- Target Species: Human
- Application: IP, Protein Purification
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- PE-A*02:01/Human SOX2 (TLMKKDKYTL) MHC Tetramer (MHC-CN0304)
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- Class: Class I
- Antigen: SOX2
- Antigen Species: Human
- Peptide: TLMKKDKYTL
- Conjugate: PE
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- APC-A*02:01/Human SOX2 (TLMKKDKYTL) MHC Tetramer (MHC-CN0303)
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- Class: Class I
- Antigen: SOX2
- Antigen Species: Human
- Peptide: TLMKKDKYTL
- Conjugate: APC
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- PE-A*02:01/Human SOX2 (SMYLPGAEV) MHC Tetramer (MHC-CN0276)
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- Class: Class I
- Antigen: SOX2
- Antigen Species: Human
- Peptide: SMYLPGAEV
- Conjugate: PE
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- APC-A*02:01/Human SOX2 (SMYLPGAEV) MHC Tetramer (MHC-CN0275)
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- Class: Class I
- Antigen: SOX2
- Antigen Species: Human
- Peptide: SMYLPGAEV
- Conjugate: APC
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- Anti-Mouse SOX2 Immunohistochemistry Kit (VS-0525-XY6822)
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- Species Reactivity: Human, Mouse, Rat
- Target: SOX2
- Application: IHC
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- Anti-SOX2 Immunohistochemistry Kit (VS-0325-XY2151)
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- Species Reactivity: Human, Mouse, Rat
- Target: SOX2
- Application: IHC
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- CytoStream™ Mouse Anti-SOX2 Recombinant Antibody (VS-0225-XY202) (VS-0225-XY202)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, kappa
- Application: FC
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- CytoStream™ Mouse Anti-SOX2 Recombinant Antibody (clone 245610) (VS-0225-XY201)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2a
- Application: FC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC, IHC-P, WB, sELISA
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- Rabbit Anti-SOX2 Recombinant Antibody (clone AFY0078) (MOR-0107-FY)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: ICC, IHC-P, WB
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- Mouse Anti-SOX2 Monoclonal Antibody (VS7-0425-WR912) (VS7-0425-WR912)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ICC, ELISA
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- Rabbit Anti-SOX2 Recombinant Antibody (VS13-YC1098) (VS13-YC1098)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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For Research Use Only. Not For Clinical Use.
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Muller glia cells, Basal squamous epithelial cells, Squamous epithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, HAP1, NTERA-2, U-251 MG)
Interaction
Interacts with ZSCAN10 (By similarity). Interacts with SOX3 and FGFR1 (By similarity). Interacts with GLIS1 (PubMed:21654807). Interacts with POU5F1; binds synergistically with POU5F1 to DNA (By similarity).
Molecular function
Activator, Developmental protein, DNA-binding
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