Afuco™ Anti-Human CD276 ADCC Recombinant Antibody (MGA271), ADCC Enhanced (CAT#: AFC-112CL)
Anti-CD276 ADCC Enhanced Antibody (MGA271) is an ADCC enhanced antibody produced by our Afuco™ platform. MGA271 is a first-in-class, humanized IgG1κ monoclonal antibody that recognizes human B7-H3, a novel member of the B7 family of immune regulators. MGA271 has been Fc-engineered to further augment its tumor killing activity.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17139/if_selected.jpg

(High expression in placenta)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17826/40943_A_1_7_val_selected.jpg

(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_5_6.jpg

(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_B_7_5.jpg

(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_9_3.jpg

(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_7_4.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103855-CD276
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Solid Tumors
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "CD276"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-117CL | Anti-Human CD276 Recombinant Antibody (TAB-117CL) | ADCC, FuncS | Antibody |
TAB-424CQ | Anti-Human CD276 Recombinant Antibody (TAB-424CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
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For Research Use Only. Not For Clinical Use.
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