Anti-Human NOTCH1 Recombinant Antibody (Brontictuzumab) (CAT#: TAB-H11)
Recombinant Humanized (from mouse) antibody to Human NOTCH1
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SDS-PAGE
Figure 1 Anti-Human NOTCH1 Recombinant Antibody in SDS-PAGE
Lane M: Protein Marker Lane 1: Non-Reducing (2.0 μg) Lane 2: Reducing (2.0 μg)
Specifications
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG2 - lambda
- Specificity
- NOTCH1 (notch 1, translocation-associated notch-1, TAN-1, TAN1) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- Inhib
- CAS
- 1447814-75-6
- Generic Name
- brontictuzumab
- Related Disease
- Lymphoma
Product Property
- Purity
- >95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Applications
- Application Notes
- The Human NOTCH1 antibody has been reported in applications of Inhibition.
Inhib: 10 mg/kg.
Target
- Alternative Names
- brontictuzumab;1447814-75-6;N248A ;NOTCH1;notch 1;Notch (Drosophila) homolog 1 (translocation associated) , Notch homolog 1, translocation associated (Drosophila) , TAN1;neurogenic locus notch homolog protein 1;Notch homolog 1, translocation-associated;tr
- Gene ID
- 4851
- UniProt ID
- P46531
Related Resources
Please refer to Brontictuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Brontictuzumab.
Breast Cancer
Endocrine Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Brontictuzumab"
Afuco™ Anti-NOTCH1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H11)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human NOTCH1
DrugMonitor™ Anti-Brontictuzumab Antibody (VS-1224-YC226)Brontictuzumab has been used in trials for treating Adenoid Cystic Carcinoma, relapsed or refractory solid tumors, and relapsed or refractory lymphoid malignancies. The DrugMonitor™ Anti-Brontictuzumab Antibody (VS-1224-YC226) is an anti-drug antibody (ADA) against Brontictuzumab. This drug-based antibody is raised in mice immunized with the Brontictuzumab. The anti-Brontictuzumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Brontictuzumab in samples.
See other products for "NOTCH1"
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-539MZ | Rat Anti-NOTCH1 Recombinant Antibody (TAB-539MZ) | WB, Competition ELISA, Neut | Rat IgG1 |
| TAB-540MZ | Rat Anti-NOTCH1 Recombinant Antibody (TAB-540MZ) | WB, Competition ELISA, Neut | Rat IgG1 |
| TAB-543MZ | Anti-Human NOTCH1 Recombinant Antibody (mAb N248A) | ELISA, WB, Luciferase reporter assay | |
| TAB-539MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-539MZ-S(P)) | WB, Competition ELISA | Rat scFv |
| TAB-540MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-540MZ-S(P)) | WB, Competition ELISA | Rat scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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