This antibody shows a neutralization activity and can inhibit Notch ligand-induced signaling with the ability to inhibit growth of HPB-ALL cells.
Figure 1 shows the results of a luciferase reporter assay comparing the antibodies N248A and A12.2.
Figure 2 shows the results of domain swap and an ELISA assay to analyze the binding epitopes of A12.2 as compared to N248A.
Figure 3 shows the analysis of the ability of A12.2 to inhibit growth of HPB-ALL cells.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H11 | Anti-Human NOTCH1 Recombinant Antibody (Brontictuzumab) | Inhib | IgG2 - lambda |
TAB-541MZ | Human Anti-NOTCH1 Recombinant Antibody (TAB-541MZ) | Neut, WB | Humanized antibody |
TAB-542MZ | Human Anti-NOTCH1 Recombinant Antibody (TAB-542MZ) | Neut, WB | Humanized antibody |
TAB-541MZ-S(P) | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-541MZ-S(P)) | WB, Competition ELISA | Humanized scFv |
TAB-542MZ-S(P) | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-542MZ-S(P)) | WB, Competition ELISA | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-660 | Human Anti-NOTCH1 Recombinant Antibody; Fab Fragment | ELISA | Human Fab |
NS-060CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2E6); Fab Fragment | FC, IF, ELISA | Mouse Fab |
NS-061CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2G10); Fab Fragment | FC, IF, ELISA | Mouse Fab |
NS-062CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2A11); Fab Fragment | FC, IF, ELISA | Mouse Fab |
HPAB-AP750-YC-F(E) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc133); Fab Fragment | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-539MZ | Rat Anti-NOTCH1 Recombinant Antibody (TAB-539MZ) | WB, Competition ELISA, Neut | Rat IgG1 |
TAB-540MZ | Rat Anti-NOTCH1 Recombinant Antibody (TAB-540MZ) | WB, Competition ELISA, Neut | Rat IgG1 |
TAB-543MZ | Anti-Human NOTCH1 Recombinant Antibody (mAb N248A) | ELISA, WB, Luciferase reporter assay | |
TAB-539MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-539MZ-S(P)) | WB, Competition ELISA | Rat scFv |
TAB-540MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-540MZ-S(P)) | WB, Competition ELISA | Rat scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-545MZ-F(E) | Anti-Human NOTCH1 Recombinant Antibody Fab Fragment (23814) | ELISA | Human antibody |
TAB-546MZ-F(E) | Anti-Human NOTCH1 Recombinant Antibody Fab Fragment (23418.8) | ELISA | Human antibody |
TAB-547MZ-F(E) | Human Anti-NOTCH1 Recombinant Antibody; Fab Fragment (TAB-547MZ-F(E)) | ELISA | Human Fab |
PABX-152 | Recombinant Human Anti-NRR1 Antibody | ELISA, Neut, FuncS | IgG |
PABX-152-F (E) | Recombinant Human Anti-NRR1 Antibody Fab Fragment | ELISA, Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1786CQ | Recombinant Mouse Anti-NOTCH1 Antibody (MHN1-519) | FC, BL | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2473 | Hi-Affi™ Recombinant Rabbit Anti-NOTCH1 Monoclonal Antibody (DS2473AB) | WB, IHC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0078-YC | Mouse Anti-NOTCH1 Recombinant Antibody (clone OMP-52M51) | IHC | Mouse IgG |
HPAB-0085-YJ | Rat Anti-NOTCH1 Recombinant Antibody (clone bTAN 20) | IF, IHC, WB | Rat IgG1, κ |
HPAB-0681-WJ | Human Anti-NOTCH1 Recombinant Antibody (clone h52M51) | ELISA, WB | Humanized IgG |
ZG-0032U | Rabbit Anti-NOTCH1 Recombinant Antibody (clone 4F6) | ELISA, WB, IHC | Rabbit IgG |
VS3-CJ976 | Rabbit Anti-NOTCH1 Recombinant Antibody (VS3-CJ976) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-060CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2E6) | FC, IF, ELISA, Inhib, FuncS | Mouse IgG1 |
NS-061CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2G10) | FC, IF, ELISA | Mouse IgG1 |
NS-062CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2A11) | FC, IF, ELISA, Inhib | Mouse IgG2b |
NS-063CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2D11); Fab Fragment | FC, IF, ELISA | Mouse Fab |
NS-063CN-S(P) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2D11); scFv Fragment | FC, IF, ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H11 | Afuco™ Anti-NOTCH1 ADCC Recombinant Antibody (Brontictuzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP750-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc133); scFv Fragment | ELISA, FC | Human scFv |
HPAB-AP751-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc155); scFv Fragment | ELISA, FC | Human scFv |
HPAB-AP752-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc49); scFv Fragment | ELISA, FC | Human scFv |
HPAB-AP753-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc104); scFv Fragment | ELISA, FC | Human scFv |
HPAB-AP754-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc629); scFv Fragment | ELISA, FC | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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