Anti-Human NOTCH1 Recombinant Antibody (A12.2) (CAT#: TAB-544MZ)
This antibody shows a neutralization activity and can inhibit Notch ligand-induced signaling with the ability to inhibit growth of HPB-ALL cells.
Specific Inquiry
FuncS
Figure 1 shows the results of a luciferase reporter assay comparing the antibodies N248A and A12.2.
ELISA
Figure 2 shows the results of domain swap and an ELISA assay to analyze the binding epitopes of A12.2 as compared to N248A.
Inhib
Figure 3 shows the analysis of the ability of A12.2 to inhibit growth of HPB-ALL cells.
Specifications
- Immunogen
- Human Notch1
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- A12.2
- Applications
- ELISA, FuncS, Inhib
- Related Disease
- T-cell acute lymphoblastic leukemia (T-ALL), breast cancer
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay, Inhibition.
Target
Related Resources
Breast Cancer
Endocrine Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone A12.2"
See other products for "NOTCH1"
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1747z | Mouse Anti-NOTCH1 Recombinant Antibody (clone 21H9) | WB, ICC, IF, IHC | Mouse IgG2b |
| PABL-666 | Human Anti-NOTCH1 Recombinant Antibody | ELISA | Human IgG |
| MOB-1438CT | Recombinant Mouse anti-Mouse NOTCH1 Monoclonal antibody (3E12) | FC | |
| HPAB-0044LY | Mouse Anti-NOTCH1 Recombinant Antibody (HPAB-0044LY) | WB | Mouse IgG1 |
| FAMAB-1388CQ | Mouse Anti-NOTCH1 Recombinant Antibody (clone E6) | Inhib, Block, ELISA, IF | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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