Anti-Human MET Recombinant Antibody (PGIA-4-A5) (CAT#: TAB-038MZ)
This antibody is specific for c-Met, a protein tyrosine kinase whose ligand is hepatocyte growth factor (HGF). The antibody may block binding of HGF to c-Met and substantially inhibit c-Met activation.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55607/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55607/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/if_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18577/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18577/if_selected.jpg
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_7_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (A-431, CAPAN-2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105976-MET
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105976-MET
Specifications
- Host Species
- Human
- Derivation
- Phagemid library
- Type
- Human antibody
- Specificity
- Human
- Clone
- PGIA-4-A5
- Applications
- Western Blot, Enzyme-linked Immunosorbent Assay
- Related Disease
- Cancer, pathological liver conditions, and ophthalmic diseases
Target
- Alternative Names
- MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase
- Gene ID
- 4233
- UniProt ID
- A0A024R759
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H24 | Anti-Human MET Recombinant Antibody (TAB-H24) | FuncS, IF, Neut, ELISA, FC, IP, WB | IgG4 - kappa |
| TAB-190-F(E) | Anti-Human Met(Onartuzumab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | Fab / Fc - G1 - kappa |
| TAB-521CL | Anti-Human MET Recombinant Antibody (TAB-521CL) | WB, FuncS | Antibody |
| TAB-026MZ | Anti-Human MET Recombinant Antibody (73R009) | WB | Humanized antibody |
| TAB-026MZ-F(E) | Anti-Human MET Recombinant Antibody Fab Fragment (73R009) | WB | Humanized antibody |
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