Recombinant Anti-human PRNP Intrabody [+36 GFP]
CAT#: IAB-B034(G)
Recombinant anti-PRNP intrabody in fusion with +36GFP works within cells to bind PRNP, expressed in CHO cells. Anti-prion intrabodies targeted to the lumen of the endoplasmic reticulum provide a simple and effective means to inhibit the transport of PrPC to the cell surface.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg
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Specifications
- Immunogen
- human prion protein
- Host Species
- mouse
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Formats of immunological tests: Western blot; Coimmunopricipation; Functional studies
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B034(A) | Recombinant Anti-human PRNP Intrabody [(D-Arg)9] | IF, FC, WB, FuncS | scFv-(D-Arg)9 |
| IAB-B034(T) | Recombinant Anti-human PRNP Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-310 | Mouse Anti-PRNP Recombinant Antibody (clone POM2); scFv Fragment | WB, IHC, FuncS | Mouse scFv |
| FAMAB-0272CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone ch31C6); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| FAMAB-0273CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 106); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| FAMAB-0274CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 110); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| FAMAB-0275CQ-S(P) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 132); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-310 | Mouse Anti-PRNP Recombinant Antibody (clone POM2); Fab Fragment | WB, IHC, FuncS | Mouse Fab |
| FAMAB-0272CQ-F(E) | Human Anti-PRNP Recombinant Antibody (clone ch31C6); Fab Fragment | ELISA, WB, IHC | Chimeric (mouse/human) Fab |
| FAMAB-0273CQ-F(E) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 106); Fab Fragment | ELISA, WB, IHC | Mouse Fab |
| FAMAB-0274CQ-F(E) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 110); Fab Fragment | ELISA, WB, IHC | Mouse Fab |
| FAMAB-0275CQ-F(E) | Mouse Anti-PRNP Recombinant Antibody (clone mAb 132); Fab Fragment | ELISA, WB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-026 | Recombinant Anti-Human PRNP VHH Single Domain Antibody (PNBL-026) | WB, ELISA, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-943LC | Anti-Mouse Prnp Recombinant Antibody (D13) | ELISA | Human antibody |
| MRO-944LC | Anti-Mouse Prnp Recombinant Antibody (D18) | ELISA | Human antibody |
| MRO-945LC | Anti-Mouse Prnp Recombinant Antibody (R72) | ELISA | Human antibody |
| MRO-946LC | Anti-Mouse Prnp Recombinant Antibody (R1) | ELISA | Human antibody |
| MRO-947LC | Anti-Mouse Prnp Recombinant Antibody (R2) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-953LC | Anti-Human PRNP Recombinant Antibody (1A1) | FuncS, FC | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-954LC | Anti-Human PRNP Recombinant Antibody (V5B2) | ELISA | Mouse antibody |
| MRO-955LC | Mouse Anti-Prnp Recombinant Antibody (MRO-955LC) | ELISA, WB | Mouse IgG |
| MRO-956LC | Mouse Anti-Prnp Recombinant Antibody (MRO-956LC) | ELISA, WB | Mouse IgG |
| MRO-957LC | Mouse Anti-Prnp Recombinant Antibody (MRO-957LC) | ELISA, WB | Mouse IgG |
| MRO-942LC-F(E) | Anti-Sheep PRNP Recombinant Antibody Fab Fragment (6.1) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0727MZ | Chicken Anti-PRNP Polyclonal IgY | ICC, IF | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-161 | Mouse Anti-PRNP Recombinant Antibody (clone POM1) | ELISA, IP, IHC, FuncS | Mouse IgG1 |
| FAMAB-0050-CN | Chicken Anti-PRNP Recombinant Antibody (clone phAb4-31) | ELISA | Chicken IgG |
| FAMAB-0051-CN | Human Anti-PRNP Recombinant Antibody (clone hu4.00) | ELISA | Humanized IgG |
| FAMAB-0052-CN | Human Anti-PRNP Recombinant Antibody (clone ch4.31) | ELISA | Chimeric (chicken/human) IgG |
| FAMAB-0053-CN | Human Anti-PRNP Recombinant Antibody (clone hu4.15) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2871 | Hi-Affi™ Recombinant Rabbit Anti-PRNP Monoclonal Antibody (DS2871AB) | WB, FC, IHC-P, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0079LC | Recombinant Mouse Anti-Sheep Prnp Antibody (12B2) | WB | IgG |
| EPAF-0087LC | Recombinant Mouse Anti-Sheep Prnp Antibody (ICSM18) | WB | IgG |
| EPAF-0136LC | Recombinant Mouse Anti-Sheep Prnp Antibody (VRQ14) | ELISA | IgG2a |
| EPAF-0594CQ | Recombinant Mouse Anti-Human PRNP Antibody (ICSM68) | ELISA | IgG |
| EPAF-0595CQ | Recombinant Mouse Anti-Human PRNP Antibody (ICSM39) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY84 | Human Anti-PRNP (clone mAb132) scFv-Fc Chimera | ELISA, WB | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1763 | Anti-PRNP Immunohistochemistry Kit | IHC | |
| VS-0525-XY5727 | Anti-Human PRNP Immunohistochemistry Kit | IHC | |
| VS-0525-XY5728 | Anti-Mouse PRNP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC520 | Recombinant Anti-PRNP Vesicular Antibody, EV Displayed (VS-0425-YC520) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC150 | Recombinant Anti-PRNP (AA 56-90 x AA 83-89) Biparatopic Antibody, Tandem scFv (mAb 106 x mAb 110) | ELISA, IHC, WB | Tandem scFv |
| VS-0525-YC152 | Recombinant Anti-PRNP (AA 119-127 x AA 143-149) Biparatopic Antibody, Tandem scFv (mAb 132 x Clone 31C6) | ELISA, IHC, WB | Tandem scFv |
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