Recombinant Mouse Anti-Sheep Prnp Antibody (VRQ14)

Name: Recombinant Mouse Anti-Sheep Prnp Antibody (VRQ14)
SKU: EPAF-0136LC
Rating: 5 (1 reviews)

CAT#: EPAF-0136LC

This product is a mouse monoclonal antibody that specifically recognizes Major prion protein precursor from Sheep. The Prnp-binding antibody VRQ14 is an epitope-specific antibody that can be used in ELISA.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg

Subcellular Location Figure 2 IHC staining of human cerebellum

Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/ihc_selected.jpg

Normal Tissue Figure 3 Cerebral cortex

Neuropil
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_B_7_5.jpg

Normal Tissue Figure 4 Caudate

Neuronal cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/95554_B_9_7.jpg

Normal Tissue Figure 5 Colon

Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_A_9_3.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (WM-115)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP

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Specifications

Host Species
Mouse

Type
IgG2a

Specificity
Major prion protein precursor

Species Reactivity
Sheep

Clone
VRQ14

Applications
Enzyme-linked Immunosorbent Assay

Related Disease
Transmissible spongiform encephalopathies

Target

Alternative Names
Prnp; Major prion protein precursor; Sheep; Sheep; Major prion protein precursor; Prnp

Gene ID
493887

UniProt ID
P23907

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - EPAF-0136LC.pdf

MSDS

MSDS - EPAF-0136LC.pdf

COA

Certificate of Analysis Lookup

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CAT
Product Name

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