Human Anti-TGFB1 Recombinant Antibody; Fab Fragment (HPAB-0495-CN-F(E)) (CAT#: HPAB-0495-CN-F(E))
This product is a recombinant human antibody Fab fragment that binds to transforming growth factor beta (TGFβ), and neutralizes TGFβ1, TGFβ2 and TGFβ3. This human pan-neutralizing anti-TGF-β monoclonal antibody can reduce auto-induced TGF-β synthesis by measuring the total renal TGF-β1 protein.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1901_C17_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1901_C17_1_selected.jpg
Figure 2 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/ihc_selected.jpg
Figure 3 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1812_G3_5_cr5a09c41109818_blue_red_green.jpg
(Immunofluorescent staining of human cell line HEL shows localization to Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73356/1812_G3_5_cr5a09c41109818_blue_red_green.jpg
Figure 4 Bone marrow
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/2675_B_6_4.jpg
(Hematopoietic cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/361/2675_B_6_4.jpg
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105329-TGFB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105329-TGFB1
Specifications
- Immunogen
- TGFβ1, TGFβ2 or TGFβ3 coupled to Dynabeads M-270 amine (Dynal)
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human TGFB1
- Species Reactivity
- Human
- Applications
- ELISA, Neut
- Related Disease
- Cancer, Fibrotic disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-98 | Mouse Anti-Tgfb1 Recombinant Antibody (clone CB57B9) | Neut, FC | Mouse IgG1, κ |
| VS3-QX1116 | Mouse Anti-TGFB1 Recombinant Antibody (clone 4C1-8C8-1E7) | IHC | Mouse IgG1 |
| VS3-QX1117 | Mouse Anti-TGFB1 Recombinant Antibody (clone 8F6-3G10-4G9) | WB, IHC | Mouse IgG1 |
| VS3-QX1118 | Mouse Anti-TGFB1 Recombinant Antibody (clone 7C9-8D7-5G1) | IHC | Mouse IgG1 |
| VS3-QX1119 | Mouse Anti-TGFB1 Recombinant Antibody (clone 3E7-G11-B7) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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