Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation) (CAT#: Gly-030LC)
This product is a human monoclonal antibody with N-glycosylation site Asn299 in the heavy chain. Antibody MORAb-003 has increased ADCC, it specifically binds human FRA and can be potentially used in the treatment of FRA-mediated disease such as cancer.
Specific Inquiry
Subcellular Location
RNA Expression

Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg

Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
Glyco-engineering
- Glycosylation site
- Asn299 of heavy chain
- Glycoform (ratio)
- M3N2F
- Glycosylation Type
- N-glycosylation
- Activity
- Increased ADCC
Specifications
- Target
- FOLR1 (Folate receptor alpha)
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Clone
- MORAb-003
- Expression Host
- CHO-K1
- Applications
- ELISA
Target
- Alternative Names
- FOLR1; folate receptor 1 (adult); FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18;
- Related Disease
- FRA-mediated disease
- Gene ID
- 2348
- UniProt ID
- A0A024R5H1
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IHC Kits & Antibodies
Biparatopic Antibodies
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B029(A) | Recombinant Anti-human FOLR1 Intrabody [(D-Arg)9] | PCA, Neut, FuncS | scFv-(D-Arg)9 |
IAB-B029(G) | Recombinant Anti-human FOLR1 Intrabody [+36 GFP] | WB, Neut, FuncS | scFv-(+36GFP) |
IAB-B029(T) | Recombinant Anti-human FOLR1 Intrabody [Tat] | WB, ICC, Neut, FuncS | scFv-Tat |
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For Research Use Only. Not For Clinical Use.
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