FOLR1

Creative Biolabs offers an extensive range of powerful recombinant antibodies targeting FOLR1, meticulously engineered for application in diverse immunological assays. Designed for high specificity and accuracy, these antibodies enable researchers to thoroughly investigate the role of FOLR1 across various biological processes, facilitating advancements in understanding and targeting this important protein in health and disease.

FOLR1: An Essential Target for Cancer Treatment

Folate Receptor 1 (FOLR1) is a cell surface protein that binds to folate, a B-vitamin essential for various biological processes. It is primarily expressed on the apical surface of epithelial cells in organs like the lung, kidney, and choroid plexus. However, its expression is significantly elevated in various solid tumors, such as high-grade osteosarcoma, breast cancer, ovarian cancer, and non-small cell lung cancer, making it a promising target for cancer diagnosis and treatment, especially for malignancies that primarily affect women.

Alternative Names

Folate receptor 1; folate binding protein; FOLR; FR-alpha; FRα; FBP; NCFTD; folate receptor 1 (adult).

Background

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Anti-FOLR1 Recombinant Antibody Products

Creative Biolabs presents an extensive range of recombinant antibodies specifically engineered for targeting FOLR1 with high precision. These versatile antibodies, available in multiple formats, boast remarkable specificity and binding strength, making them perfect for a wide array of experimental techniques such as WB, IP, IHC, ELISA, etc.

Table 1. Featured anti-FOLR1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs specializes in the development of novel therapeutic solutions in the cutting-edge field of biotechnology. Our highly qualified team combines modern research processes with cutting-edge technology to provide customized solutions for a wide range of applications. We take pride in our dedication to excellence, ensuring that every product we offer gets the highest levels of quality and performance.

Customer Reviews

Excellent

Va***i
Human Anti-FOLR1 Recombinant Antibody (TAB-016CQ) (TAB-016CQ)

I've been quite satisfied with Creative Biolabs' anti-FOLR1 recombinant antibody. The products arrived on schedule and in great shape. The antibody demonstrated high specificity and sensitivity in my WB experiments, allowing for clear and reliable detection of the target protein. The technical support team was also helpful in answering my questions and providing troubleshooting advice.

22/Oct/2021

Excellent

Go***z
Human Anti-FOLR1 Recombinant Antibody (TAB-018CQ) (TAB-018CQ)

I've utilized Creative Biolabs' anti-FOLR1 antibody in immunohistochemical investigations, and the findings have been consistently positive. The antibody exhibited strong and specific staining in the target tissue, allowing for accurate localization of the protein of interest. The antibody's stability and effectiveness have been consistent, making it a useful tool in my study.

17/Jun/2022

Excellent

Na***z
Rabbit Anti-FOLR1 Recombinant Antibody (clone R03-5I8) (VS3-XY3360)

Creative Biolabs' anti-FOLR1 recombinant antibody has proven to be an invaluable resource in our study. In our Western blot assays, the antibody displayed great specificity and sensitivity, allowing for accurate and consistent identification of the target protein. The technical support crew was responsive and gave useful assistance. We are pleased with the overall quality and performance of this product.

5/Nov/2023

Anti-FOLR1 Recombinant Antibody Production

Creative Biolabs adopts an unconventional genetic modification approach to generate customized antibodies that target the FOLR1 protein, allowing for the efficient synthesis of premium antibodies, and ensuring a constant and durable supply appropriate for a wide range of applications.

Featured Anti-FOLR1 Recombinant Antibody Production Platforms
Fig.7 Milligram-scale anti-FOLR1 recombinant antibody production.

Fig.8 Gram-scale anti-FOLR1 recombinant antibody production.

Anti-FOLR1 Recombinant Antibody Modalities

Creative Biolabs offers a diverse range of high-quality recombinant antibodies targeting FOLR1, meticulously designed to meet the unique needs of researchers. These antibodies come in various formats, ensuring flexibility and adaptability for different experimental applications.

Fig.9 Full-length anti-FOLR1 recombinant antibody production and modalities.

FOLR1-Targeted Drug Information

Public Drug Information Targeting FOLR1

Table 2. Public drug targeting FOLR1.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Please contact us if you're looking for a high-quality anti-FOLR1 recombinant product.