Products
Loading...

FOLR1

More+
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, IHC, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
RIA, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, WB, FuncS
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
FC, IP, ELISA, Neut, FuncS, IF, ICC
Targets:
FOLR1 & CD3
Type:
BiTE
Application:
FuncS, Promising therapeutic agent
Targets:
CD28 & FOLR1
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
FOLR1 & CD3
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Targets:
FOLR1 & CD3
Type:
TandAb
Application:
FuncS, Promising therapeutic agent
Target:
FOLR1
Linker:
sulfo-SPDB
Drug:
DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Target:
FOLR1
Linker:
sulfo-SPDB (sulfosuccinimidyl N-succinimidyl-4-(2-pyridyldithio)butyrate)
Drug:
DM4 (N2'-Deacetyl-N2'-(4-mercapto-4- methyl-1-oxopentyl)maytansine)
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA, FC, WB
Species Reactivity:
Human, Cynomolgus monkey
Application:
ELISA, WB, IHC
Species Reactivity:
Human, Cynomolgus monkey
Type:
Chimeric antibdy (rat/human)
Application:
ELISA, WB, IHC
Species Reactivity:
Human, Cynomolgus monkey
Type:
Humanized antibody
Application:
ELISA, WB, IHC
Species Reactivity:
Human
Application:
ELISA, FC, WB, IHC
Species Reactivity:
Human, Cynomolgus monkey
Type:
Human antibody
Application:
IHC
Host animal:
Human
Specificity:
Human
Type:
Human antibody
Classification:
Fc glycosylation/Non fucosylated
Glycosylation site:
Asn299 of heavy chain
Glycoform (ratio):
NGA2
Host animal:
Human
Specificity:
Human
Type:
Human antibody
Classification:
Fc glycosylation/Non fucosylated
Glycosylation site:
Asn299 of heavy chain
Glycoform (ratio):
NGA2
Host animal:
Human
Specificity:
Human
Type:
Human antibody
Classification:
Fc glycosylation
Glycosylation site:
Asn299 of heavy chain
Glycoform (ratio):
M3N2F
Host animal:
Human
Specificity:
Human
Type:
Human antibody
Classification:
Fc glycosylation
Glycosylation site:
Fc region
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA, FC, WB
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-381-2994    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2018 Creative-Biolabs All Rights Reserved