Recombinant Anti-human FOLR1 Intrabody [+36 GFP]
CAT#: IAB-B029(G)
Recombinant anti-FOLR1 intrabody in fusion with +36GFP works within cells to bind FOLR1, which is selectively overexpressed in 90% of nonmucinous ovarian carcinomas, expressed in CHO cells. FR expression is associated with tumor progression and affects cell proliferation and the intracellular expression of single-chain (sc) antibodiess (intrabody) can downmodulate membrane expression of FR in ovary cancer cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
❮
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Specifications
- Immunogen
- human folate receptor 1 (adult)
- Host Species
- mouse
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Formats of immunological tests: Western blot; Neutralization; Functional studies
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- FOLR1; folate receptor 1 (adult); FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18
- Gene ID
- 2348
- UniProt ID
- A0A024R5H1
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1297z | Mouse Anti-FOLR1 Recombinant Antibody (clone 24A8) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2a |
| HPAB-0115-CN | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0115-CN) | ELISA, FC, IHC | Mouse IgG2b |
| HPAB-0116-CN | Human Anti-FOLR1 Recombinant Antibody (HPAB-0116-CN) | ELISA, FC, IHC | Humanized IgG1 |
| HPAB-0117-CN | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0117-CN) | ELISA, FC | Mouse IgG |
| HPAB-0118-CN | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0118-CN) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B029(A) | Recombinant Anti-human FOLR1 Intrabody [(D-Arg)9] | PCA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B029(T) | Recombinant Anti-human FOLR1 Intrabody [Tat] | WB, ICC, Neut, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-113 | Anti-Human folate receptor 1 Recombinant Antibody (TAB-113) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
| TAB-019CQ | Human Anti-FOLR1 Recombinant Antibody (TAB-019CQ) | ELISA, WB, IHC | Human IgG1, κ |
| TAB-019CQ-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-019CQ-S(P)) | ELISA, WB, IHC | Human scFv |
| TAB-019CQ-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-019CQ-F(E)) | ELISA, WB, IHC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-016CQ | Human Anti-FOLR1 Recombinant Antibody (TAB-016CQ) | ELISA, FC, WB | Human IgG |
| TAB-016CQ-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-016CQ-S(P)) | ELISA, FC, WB | Human scFv |
| TAB-382CQ | Anti-Human FOLR1 Recombinant Antibody (TAB-382CQ) | IHC | Human antibody |
| TAB-382CQ-S(P) | Anti-Human FOLR1 Recombinant Antibody scFv Fragment (TAB-382CQ-S(P)) | IHC | Human antibody |
| TAB-382CQ-F(E) | Anti-Human FOLR1 Recombinant Antibody Fab Fragment (TAB-382CQ-F(E)) | IHC | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-017CQ | Rat Anti-FOLR1 Recombinant Antibody (TAB-017CQ) | ELISA, WB, IHC | Rat IgG1, κ |
| TAB-020CQ | Mouse Anti-FOLR1 Recombinant Antibody (TAB-020CQ) | ELISA, FC, WB, IHC | Mouse IgG1 |
| TAB-017CQ-S(P) | Rat Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-017CQ-S(P)) | ELISA, WB, IHC | Rat scFv |
| TAB-017CQ-F(E) | Rat Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-017CQ-F(E)) | ELISA, WB, IHC | Rat Fab |
| TAB-020CQ-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-020CQ-F(E)) | ELISA, FC, WB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018CQ | Human Anti-FOLR1 Recombinant Antibody (TAB-018CQ) | ELISA, WB, IHC | Chimeric (Rat/Human) IgG1, κ |
| TAB-018CQ-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-018CQ-S(P)) | ELISA, WB, IHC | Human scFv |
| TAB-018CQ-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-018CQ-F(E)) | ELISA, WB, IHC | Chimeric (Rat/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-029LC | Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-030LC | Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation) | ELISA | Human antibody |
| Gly-116LC | Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-029LC-1 | Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1333 | Hi-Affi™ Rabbit Anti-FOLR1 Recombinant Antibody (clone DS1333AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0115-CN-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0115-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0116-CN-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0116-CN-S(P)) | ELISA, FC, IHC | Humanized scFv |
| HPAB-0117-CN-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0117-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0118-CN-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0118-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0119-CN-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0119-CN-S(P)) | ELISA, FC, IHC, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0115-CN-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0115-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0116-CN-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0116-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
| HPAB-0117-CN-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0117-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0118-CN-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0118-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0119-CN-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0119-CN-F(E)) | ELISA, FC, IHC, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-113 | Afuco™ Anti-FOLR1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-113) | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0049 | APC-A*02:01/Human FBP (EIWTHSYKV) MHC Tetramer | FCM | |
| MHC-CN0685 | PE-A*02:01/Human FOLR1 (EIWTHSYKV) MHC Tetramer | FCM, IHC | |
| MHC-CN0686 | APC-A*02:01/Human FOLR1 (EIWTHSYKV) MHC Tetramer | FCM, IHC | |
| MHC-CN0687 | FITC-A*02:01/Human FOLR1 (EIWTHSYKV) MHC Tetramer | FCM, IHC | |
| MHC-CN0688 | A*02:01/Human FOLR1 (EIWTHSYKV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY70 | Human Anti-FOLR1 (clone Farletuzumab) scFv-Fc Chimera | ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC262 | Recombinant Anti-FOLR1 Vesicular Antibody, EV Displayed (VS-0425-YC262) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2606 | Anti-FOLR1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC13 | Recombinant Anti-FOLR1 Biparatopic Antibody, Asymmetric scFv-Fab | ELISA | Asymmetric scFv-Fab |
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